Thermophilic PHP Protein Tyrosine Phosphatases (Cap8C and Wzb) from Mesophilic Bacteria.

Adepeju Aberuagba, Enoch B Joel, Adebayo J Bello, Adedoyin Igunnu, Sylvia O Malomo, Femi J Olorunniji

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Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Adepeju AberuagbaSchool of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.

Enoch B JoelSchool of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.ORCID 0000-0002-6031-7558

Adebayo J BelloSchool of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.ORCID 0000-0002-6731-2047

Adedoyin IgunnuDepartment of Biochemistry, Faculty of Life Sciences, University of Ilorin, Ilorin 234031, Nigeria.

Sylvia O MalomoDepartment of Biochemistry, Faculty of Life Sciences, University of Ilorin, Ilorin 234031, Nigeria.

Femi J OlorunnijiSchool of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.ORCID 0000-0001-9389-2981

Liverpool John Moores University · GBUniversity of Ilorin · NGUniversity of Jos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein tyrosine phosphatases (PTPs) of the polymerase and histidinol phosphatase (PHP) superfamily with characteristic phosphatase activity dependent on divalent metal ions are found in many Gram-positive bacteria. Although members of this family are co-purified with metal ions, they still require the exogenous supply of metal ions for full activation. However, the specific roles these metal ions play during catalysis are yet to be well understood. Here, we report the metal ion requirement for phosphatase activities of

Indexed as

Protein Tyrosine PhosphatasesStaphylococcus aureusBacteriaIonsMetalsIonsMetalsProtein Tyrosine PhosphatasesCap8Cmetal ion activationpolymerase and histidinol phosphatasesprotein tyrosine phosphatasesthermophilic enzymesWzb

Identifiers

PMID38279261

DOI10.3390/ijms25021262

PMCPMC10816263

OpenAlexW4391023734

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.