Evidence map›Paper›PMID 38279127›Full record

ArticleBMC medical imaging2024

Performance of node reporting and data system (node-RADS): a preliminary study in cervical cancer.

Qingxia Wu, Jianghua Lou, Jinjin Liu, Linxiao Dong, Qingxia Wu, Yaping Wu, Xuan Yu, Meiyun Wang

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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  6. Node-RADS in cervical cancer: a multi-reader agreement and diagnostic performance study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Qingxia WuDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Jianghua LouDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Jinjin LiuDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Linxiao DongDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Qingxia WuBeijing United Imaging Research Institute of Intelligent Imaging, United Imaging Intelligence (Beijing) Co., Ltd., Beijing, 100089, China.
Yaping WuDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Xuan YuDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China.
Meiyun WangDepartment of Medical Imaging, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, No. 7 Weiwu Road, Zhengzhou, Henan, 450003, China. mywang@zzu.edu.cn.
Henan University · CNZhengzhou University · CNHenan Academy of Sciences · CNUnited Imaging Healthcare (China) · CN

Funding

Joint Fund of Henan Province Science and Technology R&D Program 225200810062Medical Science and Technology Research Project of Henan Province LHGJ20220057National Key R&D Program of China 2023YFC2414200National Natural Science Foundation of China 82001783National Natural Science Foundation of China 82371934
6 · The paper itself

Abstract

backgroundNode Reporting and Data System (Node-RADS) was proposed and can be applied to lymph nodes (LNs) across all anatomical sites. This study aimed to investigate the diagnostic performance of Node-RADS in cervical cancer patients.

methodsA total of 81 cervical cancer patients treated with radical hysterectomy and LN dissection were retrospectively enrolled. Node-RADS evaluations were performed by two radiologists on preoperative MRI scans for all patients, both at the LN level and patient level. Chi-square and Fisher's exact tests were employed to evaluate the distribution differences in size and configuration between patients with and without LN metastasis (LNM) in various regions. The receiver operating characteristic (ROC) and the area under the curve (AUC) were used to explore the diagnostic performance of the Node-RADS score for LNM.

resultsThe rates of LNM in the para-aortic, common iliac, internal iliac, external iliac, and inguinal regions were 7.4%, 9.3%, 19.8%, 21.0%, and 2.5%, respectively. At the patient level, as the NODE-RADS score increased, the rate of LNM also increased, with rates of 26.1%, 29.2%, 42.9%, 80.0%, and 90.9% for Node-RADS scores 1, 2, 3, 4, and 5, respectively. At the patient level, the AUCs for Node-RADS scores > 1, >2, > 3, and > 4 were 0.632, 0.752, 0.763, and 0.726, respectively. Both at the patient level and LN level, a Node-RADS score > 3 could be considered the optimal cut-off value with the best AUC and accuracy.

conclusionsNode-RADS is effective in predicting LNM for scores 4 to 5. However, the proportions of LNM were more than 25% at the patient level for scores 1 and 2, which does not align with the expected very low and low probability of LNM for these scores.

Indexed as

Uterine Cervical NeoplasmsFemaleHumansLymphatic MetastasisLymph NodesMagnetic Resonance ImagingRetrospective StudiesCervical cancerLymph nodeMetastasisMRI

Identifiers

PMID38279127
PMCPMC10811875
OpenAlexW4391262222

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.