Evidence map›Paper›PMID 38279121›Full record

ArticleBMC public health2024

Prevalence, associated factors, and gene polymorphisms of obesity in Tibetan adults in Qinghai, China.

Ye Wang, Li Pan, Huijing He, Zhanquan Li, Sen Cui, Airong Yang, Wenfang Li, Guoqiang Jia, Ximing Han, Xianghua Wang and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ye WangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li PanDepartment of Epidemiology and Statistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, 5 Dong Dan San Tiao, Dong Cheng District, Beijing, 100005, China.
Huijing HeDepartment of Epidemiology and Statistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, 5 Dong Dan San Tiao, Dong Cheng District, Beijing, 100005, China.
Zhanquan LiQinghai University Affiliated Hospital, Qinghai, China.
Sen CuiQinghai University Affiliated Hospital, Qinghai, China.
Airong YangQinghai University Affiliated Hospital, Qinghai, China.
Wenfang LiQinghai University Affiliated Hospital, Qinghai, China.
Guoqiang JiaQinghai University Affiliated Hospital, Qinghai, China.
Ximing HanQinghai University Affiliated Hospital, Qinghai, China.
Xianghua WangInstitute of Biomedical Engineering, Chinese Academy of Medical Sciences, Peking Union Medical College, 236 Baidi Road, Nankai District, Tianjin, 300192, China. xianghua126@163.com.
Guangliang ShanSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. guangliang_shan@163.com.

Funding

Key Basic Research Program of the Ministry of Science and Technology of China 2013FY114100
6 · The paper itself

Abstract

objectivesTo explore the prevalence and associated factors of obesity in Tibetan adults in Qinghai, China, and to determine the association between the FTO (rs1121980 and rs17817449) and MC4R gene (rs17782313 and rs12970134) polymorphisms with obesity.

methodsA cross-sectional survey was conducted in 2015 in Qinghai to selected Tibetan adults aged 20 to 80 years. Prevalence of obesity (BMI ≥ 28 kg/m

resultsA total of 1741 Tibetan adults were enrolled. The age- and sex- standardized prevalence of obesity and overweight was 18.09% and 31.71%, respectively. Male sex, older age, heavy level of leisure-time exercise, current smoke, and heavy level of occupational physical activity were associated with both obesity and overweight. MC4R gene polymorphisms were associated with obesity in Tibetan adults. No significant gene-environment interaction was detected.

conclusionThe prevalence of obesity and overweight in Tibetan adults was high. Both environmental and genetic factors contributed to the obesity prevalent.

Indexed as

Genetic Predisposition to DiseaseOverweightAdultAlpha-Ketoglutarate-Dependent Dioxygenase FTOBody Mass IndexCross-Sectional StudiesHumansMaleObesityPolymorphism, Single NucleotidePrevalenceTibetAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanEnvironmental factorsGenetic epidemiologyObesityPrevalenceTibetan

Identifiers

PMID38279121
PMCPMC10811834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.