ArticleNPJ digital medicine2024
Feasibility of combining spatial computing and AI for mental health support in anxiety and depression.
Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Empathic AI for Patient-Centered Cancer Care: A Scoping Review of Patient Navigation, Support, and Clinical Practice.JMIR cancer · 2026Article
- Systematic Review of Artificial Intelligence in Positive and Existential Psychiatry: Advancing Mental and Emotional Health Through Metacompetency Development.Healthcare (Basel, Switzerland) · 2026Review
- Immersive competence as a source of bias in virtual reality clinical assessment.NPJ digital medicine · 2026Article
- Digital Therapeutics and Blended Care in Major Depressive Disorder: Current Evidence and Future Directions.Advances in experimental medicine and biology · 2026Review
- Expert Consensus Best Practices for the Safe, Ethical, and Effective Design and Implementation of Artificially Intelligent Conversational Agent (i.e., Chatbot/Virtual Human) Systems in Health Care Applications.Journal of medical extended reality · 2025Article
- Graph retrieval augmented large language models for facial phenotype associated rare genetic disease.NPJ digital medicine · 2025Article
- The evolving field of digital mental health: current evidence and implementation issues for smartphone apps, generative artificial intelligence, and virtual reality.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- A scoping review of large language models for generative tasks in mental health care.NPJ digital medicine · 2025Article
- Revealing Patient Dissatisfaction With Health Care Resource Allocation in Multiple Dimensions Using Large Language Models and the International Classification of Diseases 11th Revision: Aspect-Based Sentiment Analysis.Journal of medical Internet research · 2025Article
- The role of virtual reality in managing inflammatory bowel disease: a novel approach to bridging mental and physical health.Journal of the Canadian Association of Gastroenterology · 2025Article
- American Medical Extended Reality Association Expert Consensus: Best Practices for Patient and Public Involvement in Medical Extended Reality Research.Journal of medical extended reality · 2025Article
- The Role of Virtual Reality in Chronic Pain and Loneliness: Narrative Review.Journal of medical extended reality · 2025Review
- Digital psychiatry: concepts, framework, and implications.Frontiers in psychiatry · 2025Review
- A Bibliometric Study of the Evidence About Applying Virtual Reality in Mental Health Care.Journal of multidisciplinary healthcare · 2025Review
- Psychiatry in the age of AI: transforming theory, practice, and medical education.Frontiers in public health · 2025Review
- Toward emotional mediation: generative AI in art therapy for psychosocial health support.Frontiers in public health · 2025Article
- Latent Profile Analysis and Influencing Factors Associated with the Coping Styles of Dyspnea-Related Fear Among Patients with Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Empowering tomorrow's public health researchers and clinicians to develop digital health interventions using chatbots, virtual reality, and other AI technologies.Frontiers in public health · 2025Article
- Evaluating for Evidence of Sociodemographic Bias in Conversational AI for Mental Health Support.Cyberpsychology, behavior and social networking · 2025Article
- The Feasibility and Usability of an Artificial Intelligence-Enabled Conversational Agent in Virtual Reality for Patients with Alcohol-Associated Cirrhosis: A Multi-Methods Study.Journal of medical extended reality · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing need for mental health support and a shortage of therapists have led to the development of the eXtended-reality Artificial Intelligence Assistant (XAIA). This platform combines spatial computing, virtual reality (VR), and artificial intelligence (AI) to provide immersive mental health support. Utilizing GPT-4 for AI-driven therapy, XAIA engaged participants with mild-to-moderate anxiety or depression in biophilic VR environments. Speaking with an AI therapy avatar in VR was considered acceptable, helpful, and safe, with participants observed to engage genuinely with the program. However, some still favored human interaction and identified shortcomings with using a digital VR therapist. The study provides initial evidence of the acceptability and safety of AI psychotherapy via spatial computing, warranting further research on technical enhancements and clinical impact.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.