Evidence map›Paper›PMID 38279029›Full record

ArticleLab animal2024

Open-source versatile 3D-print animal conditioning platform design for in vivo preclinical brain imaging in awake mice and anesthetized mice and rats.

Zakia Ben Youss, Tanzil Mahmud Arefin, Sawwal Qayyum, Runjie Yi, Jiangyang Zhang, Youssef Zaim Wadghiri, Leeor Alon, Omid Yaghmazadeh

Abstract read
In one paragraph

Article in Lab animal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. An Overview of Anesthetic Procedures for Ferret (Mustela putorius furo) Preclinical Brain MRI: A Call for Standardization.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zakia Ben Youss *Bernard and Irene Schwartz Center for Biomedical Imaging (CBI), Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, USA.
Tanzil Mahmud Arefin *Center for Neurotechnology in Mental Health Research, Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, USA.
Sawwal QayyumDepartment of Radiology, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0001-7782-5738
Runjie YiNeuroscience Institute, New York University School of Medicine, New York, NY, USA.
Jiangyang ZhangBernard and Irene Schwartz Center for Biomedical Imaging (CBI), Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, USA.
Youssef Zaim WadghiriBernard and Irene Schwartz Center for Biomedical Imaging (CBI), Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, USA. Youssef.ZaimWadghiri@nyulangone.org.ORCID 0000-0001-7175-9397
Leeor AlonBernard and Irene Schwartz Center for Biomedical Imaging (CBI), Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, USA. Leeor.Alon@nyulangone.org.ORCID 0000-0003-3566-9276
Omid Yaghmazadeh *Neuroscience Institute, New York University School of Medicine, New York, NY, USA. Omid.Yaghmazadeh@gmail.com.ORCID 0000-0002-2378-3605

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL, HOCHMAN, JUDITH S · 2012 to 2014
$16.8M
NRSA Training CoreTL1TR001447 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MICOLI, KEITH J. · 2015 to 2025
$5.9M
Transformation of Neuronal Activity in the Entorhinal-hippocampal-neocortex PathR01MH122391 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BASU, JAYEETA, BUZSAKI, GYORGY · 2020 to 2024
$3.3M
Non-invasive Radio Frequency Stimulation of Neurons and NetworksR01NS113782 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BUZSAKI, GYORGY, SODICKSON, DANIEL K · 2020 to 2024
$3.2M
7T Small Animal MRI Scanner Replacement for Translational Imaging ResourceS10OD018337 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BOADA, FERNANDO E · 2014 to 2014
$2.0M
NCATS NIH HHS TL1 TR001447NCATS NIH HHS UL1 TR000038NCI NIH HHS P30 CA016087NIBIB NIH HHS P41 EB017183NIH HHS S10 OD018337NIMH NIH HHS R01 MH122391NINDS NIH HHS R01 NS113782
6 · The paper itself

Abstract

Proper animal conditioning is a key factor in the quality and success of preclinical neuroimaging applications. Here, we introduce an open-source easy-to-modify multimodal 3D printable design for rodent conditioning for magnetic resonance imaging (MRI) or other imaging modalities. Our design can be used for brain imaging in anesthetized or awake mice, and in anesthetized rats. We show ease of use and reproducibility of subject conditioning with anatomical T2-weighted imaging for both mice and rats. We also demonstrate the application of our design for awake functional MRI in mice using both visual evoked potential and olfactory stimulation paradigms. In addition, using a combined MRI, positron emission tomography and X-ray computed tomography experiment, we demonstrate that our proposed cradle design can be utilized for multiple imaging modalities.

Indexed as

Evoked Potentials, VisualWakefulnessAnimalsBrainMagnetic Resonance ImagingMiceNeuroimagingPositron-Emission TomographyRatsReproducibility of Results

Identifiers

PMID38279029
PMCPMC11095950

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.