Evidence map›Paper›PMID 38279012›Full record

ArticleAnalytical and bioanalytical chemistry2024

Comprehensive metabolome characterization and comparison between two sources of Dragon's blood by integrating liquid chromatography/mass spectrometry and chemometrics.

Jia Lou, Xiao-Yan Xu, Bei Xu, Hong-da Wang, Xue Li, He Sun, Xin-Yuan Zheng, Jun Zhou, Ya-Dan Zou, Hong-Hua Wu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Separative Techniques Coupled to Mass Spectrometry for Metabolomic Analysis.Advances in experimental medicine and biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jia LouHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Xiao-Yan XuHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Bei XuHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Hong-da WangHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Xue LiHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
He SunHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Xin-Yuan ZhengTianjin Institute for Drug Control, 98 Guizhou Road, Tianjin, 300070, China.
Jun ZhouTianjin Institute for Drug Control, 98 Guizhou Road, Tianjin, 300070, China.
Ya-Dan ZouHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Hong-Hua WuHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Yue-Fei WangHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China.
Wen-Zhi YangHaihe Laboratory of Modern Chinese Medicine, 10 Poyanghu Road, Tianjin, 301617, China. wzyang0504@tjutcm.edu.cn.

Funding

Foundation of State Key Laboratory of Component-based Chinese Medicine CBCM2023202Foundation of State Key Laboratory of Component-based Chinese Medicine CBQM2022103National Natural Science Foundation of China 82374030Science & Technology Program of Haihe Laboratory of Modern Chinese Medicine 22HHZYSS00012
6 · The paper itself

Abstract

Dragon's Blood (DB) serves as a precious Chinese medicine facilitating blood circulation and stasis dispersion. Daemonorops draco (D. draco; Qi-Lin-Jie) and Dracaena cochinchinensis (D. cochinchinenesis; Long-Xue-Jie) are two reputable plant sources for preparing DB. This work was designed to comprehensively characterize and compare the metabolome differences between D. draco and D. cochinchinenesis, by integrating liquid chromatography/mass spectrometry and untargeted metabolomics analysis. Offline two-dimensional liquid chromatography/ion mobility-quadrupole time-of-flight mass spectrometry (2D-LC/IM-QTOF-MS), by utilizing a powerful hybrid scan approach, was elaborated for multicomponent characterization. Configuration of an XBridge Amide column and an HSS T3 column in offline mode exhibited high orthogonality (A

Indexed as

ChemometricsMetabolomePlant ExtractsChromatography, High Pressure LiquidChromatography, LiquidMass Spectrometrydragon's bloodPlant Extracts2D-LC/IM-QTOF-MSDaemonorops dracoDracaena cochinchinensisHybrid scan approachUntargeted metabolomics

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.