Evidence map›Paper›PMID 38278990›Full record

ArticleNature medicine2024

Hypertension care cascades and reducing inequities in cardiovascular disease in low- and middle-income countries.

Dorit Talia Stein, Marissa B Reitsma, Pascal Geldsetzer, Kokou Agoudavi, Krishna Kumar Aryal, Silver Bahendeka, Luisa C C Brant, Farshad Farzadfar, Mongal Singh Gurung, David Guwatudde and 18 more

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In one paragraph

Article in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
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  6. Hypertension awareness, treatment, control, and prognosis: insights from the sub-cohort of China PEACE million persons project.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 15 countries.

Dorit Talia SteinDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-9938-3272
Marissa B ReitsmaDepartment of Health Policy, Stanford School of Medicine, Stanford University, Stanford, CA, USA.
Pascal GeldsetzerDivision of Primary Care and Population Health, Stanford University, Stanford, CA, USA.
Kokou AgoudaviNoncommunicable Disease Program, Ministry of Health, Lomé, Togo.
Krishna Kumar AryalBergen Centre for Ethics and Priority Setting in Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.ORCID 0000-0003-0801-0775
Silver BahendekaMKPGMS-Uganda Martyrs University, Kampala, Uganda.ORCID 0000-0001-8080-7872
Luisa C C BrantFaculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-7317-1367
Farshad FarzadfarNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mongal Singh GurungPolicy and Planning Division, Ministry of Health, Thimphu, Bhutan.
David GuwatuddeDepartment of Epidemiology and Biostatistics, School of Public Health, Makerere University, Kampala, Uganda.
Yessito Corine Nadège HouehanouNational School of Public Health, University of Parakou, Parakou, Benin.
Deborah Carvalho MaltaDepartment Maternal Child and Public Health, Nursing School, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-8214-5734
João Soares MartinsFaculty of Medicine and Health Sciences, Universidade Nacional Timor Lorosa'e, Díli, Timor-Leste.
Sahar Saeedi MoghaddamEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Kibachio Joseph MwangiWorld Health Organization, Pretoria, South Africa.ORCID 0000-0003-3725-1762
Bolormaa NorovNutrition Department, National Center for Public Health, Ulaanbaatar, Mongolia.ORCID 0000-0001-8074-9393
Lela SturuaNational Center for Disease Control and Public Health, Tbilisi, Georgia.
Zhaxybay ZhumadilovSchool of Medicine, Nazarbayev University, Astana, Kazakhstan.ORCID 0009-0001-0433-8290
Till BärnighausenHeidelberg Institute of Global Health, Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.
Justine I DaviesInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
David FloodDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Maja E MarcusBrigham and Women's Hospital, Boston, MA, USA.
Michaela TheilmannHeidelberg Institute of Global Health, Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.ORCID 0000-0003-3413-232X
Sebastian VollmerDepartment of Economics & Centre for Modern Indian Studies, University of Göttingen, Göttingen, Germany.ORCID 0000-0002-7863-0462
Jennifer Manne-GoehlerDivision of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, USA.
Rifat AtunDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-1531-5983
Nikkil SudharsananHeidelberg Institute of Global Health, Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany.ORCID 0000-0003-1710-4634
Stéphane VerguetDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA. verguet@hsph.harvard.edu.ORCID 0000-0003-4128-0849
Heidelberg University · DEBrigham and Women's Hospital · USHarvard University · USUniversidade Federal de Minas Gerais · BRChan Zuckerberg Initiative (United States) · USHarvard Global Health Institute · USKiel Institute for the World Economy · DEMakerere University · UGMinistry of Health · KENational Center for Communicable Diseases · MNNational Center for Disease Control and Public Health · GENazarbayev University · KZStanford University · USStellenbosch University · ZATehran University of Medical Sciences · IRTogolese Ministry of Health · TGUganda Martyrs University · UGUniversidade da Paz · TLUniversité de Parakou · BJUniversity of Bergen · NO

Funding

World Health Organization 001
6 · The paper itself

Abstract

Improving hypertension control in low- and middle-income countries has uncertain implications across socioeconomic groups. In this study, we simulated improvements in the hypertension care cascade and evaluated the distributional benefits across wealth quintiles in 44 low- and middle-income countries using individual-level data from nationally representative, cross-sectional surveys. We raised diagnosis (diagnosis scenario) and treatment (treatment scenario) levels for all wealth quintiles to match the best-performing country quintile and estimated the change in 10-year cardiovascular disease (CVD) risk of individuals initiated on treatment. We observed greater health benefits among bottom wealth quintiles in middle-income countries and in countries with larger baseline disparities in hypertension management. Lower-middle-income countries would see the greatest absolute benefits among the bottom quintiles under the treatment scenario (29.1 CVD cases averted per 1,000 people living with hypertension in the bottom quintile (Q1) versus 17.2 in the top quintile (Q5)), and the proportion of total CVD cases averted would be largest among the lowest quintiles in upper-middle-income countries under both diagnosis (32.0% of averted cases in Q1 versus 11.9% in Q5) and treatment (29.7% of averted cases in Q1 versus 14.0% in Q5) scenarios. Targeted improvements in hypertension diagnosis and treatment could substantially reduce socioeconomic-based inequalities in CVD burden in low- and middle-income countries.

Indexed as

Cardiovascular DiseasesHypertensionCross-Sectional StudiesDeveloping CountriesHumans

Identifiers

PMID38278990
OpenAlexW4391258673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.