Evidence map›Paper›PMID 3827877›Full record

ArticleThe Biochemical journal1986

Tissue distribution of rat glutathione transferase subunit 7, a hepatoma marker.

S E Pemble, J B Taylor, B Ketterer

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
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  12. Glutathione S-transferases and hepatocarcinogenesis.Japanese journal of cancer research : Gann · 1988
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S E Pemble
J B Taylor
B Ketterer
Courtauld Institute of Art · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyadenylated RNA isolated from NN-dimethyl-4-aminoazobenzene-induced rat hepatoma was used to prepare a cDNA library in lambda gt10. Full-length clones complementary to mRNA coding for glutathione transferase subunit 7 were isolated and one of these clones (pGSTr7) was fully characterized. In Northern blot analysis, mRNA hybridizing to 32P-labelled pGSTr7 was found in poly(A)-containing RNA isolated from seven normal rat tissues but not from testis and liver. A similar hybridizing mRNA species was also detected in human placental mRNA. The same probe, used in a Southern blot analysis of genomic DNA, suggests the presence of a multigene family in the rat.

Indexed as

AnimalsBase SequenceCloning, MolecularDNAElectrophoresis, Agar GelGlutathione TransferaseLiver Neoplasms, ExperimentalMaleNucleic Acid HybridizationRatsRats, Inbred StrainsRNA, MessengerTissue DistributionDNAGlutathione TransferaseRNA, Messenger

Identifiers

PMID3827877
PMCPMC1147502
OpenAlexW2344678176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.