ArticleScience advances2024
The missing third dimension-Functional correlations of BOLD signals incorporating white matter.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Mapping the functional connectome between grey matter and white matter.Communications biology · 2026Article
- Developmental changes of the white matter functional connectome.Molecular psychiatry · 2026Article
- A multi-modal parcellation of human globus pallidus and its implications for symptom prediction and stratification in Parkinson's disease.BMC medicine · 2026Article
- The nature and interpretation of BOLD signals in white matter - A review.Magnetic resonance imaging · 2026Review
- Abnormal signal transmission in white matter revealed by resting-state communication connectivity in Alzheimer's disease: A comprehensive cross-sectional and longitudinal study.Translational psychiatry · 2026Article
- White-Matter BOLD Mediates Time-Varying Cortico-Cortical Functional Connectivity.bioRxiv : the preprint server for biology · 2025Article
- GWM-HFN, a Gray-White Matter heterogeneous fusion network for functional connectomes.Communications biology · 2025Article
- Integrating direct electrical stimulation with brain connectivity predicts lesion-induced language impairment and recovery.Communications medicine · 2025Article
- Mapping grey and white matter activity in the human brain with isotropic ADC-fMRI.Nature communications · 2025Article
- Myelination selectively modulates BOLD signal in white matter.Research square · 2025Article
- Functional connectivity between the uncinate fasciculus and frontotemporal semantic system supports reading comprehension in adolescents.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Structure-function coupling in white matter uncovers the hypoconnectivity in autism spectrum disorder.Molecular autism · 2024Article
- Towards Comprehensive Connectivity Modeling.Neuroinformatics · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Correlations between magnetic resonance imaging (MRI) blood oxygenation level-dependent (BOLD) signals from pairs of gray matter areas are used to infer their functional connectivity, but they are unable to describe how white matter is engaged in brain networks. Recently, evidence that BOLD signals in white matter are robustly detectable and are modulated by neural activities has accumulated. We introduce a three-way correlation between BOLD signals from pairs of gray matter volumes (nodes) and white matter bundles (edges) to define the communication connectivity through each white matter bundle. Using MRI images from publicly available databases, we show, for example, that the three-way connectivity is influenced by age. By integrating functional MRI signals from white matter as a third component in network analyses, more comprehensive descriptions of brain function may be obtained.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.