Evidence map›Paper›PMID 38277368›Full record

ArticlePloS one2024

Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction.

Cenjing Zhu, Rachel P Dreyer, Fan Li, Erica S Spatz, César Caraballo, Shiwani Mahajan, Valeria Raparelli, Erica C Leifheit, Yuan Lu, Harlan M Krumholz and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Cenjing ZhuDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States of America.ORCID 0000-0003-1803-0059
Rachel P DreyerDepartment of Emergency Medicine, Yale School of Medicine, New Haven, CT, United States of America.
Fan LiDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, United States of America.ORCID 0000-0001-6183-1893
Erica S SpatzDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States of America.
César CaraballoCenter for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, CT, United States of America.
Shiwani MahajanCenter for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, CT, United States of America.
Valeria RaparelliDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Erica C LeifheitDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States of America.
Yuan LuCenter for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, CT, United States of America.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, CT, United States of America.ORCID 0000-0003-2046-127X
John A SpertusHealthcare Institute for Innovations in Quality, University of Missouri-Kansas City, Kansas City, Missouri, United States of America.
Gail D'OnofrioDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States of America.
Louise PiloteCenter for Outcomes Research and Evaluation, Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.
Judith H LichtmanDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States of America.ORCID 0000-0001-5362-3875
Yale University · USMcGill University Health Centre · CASaint Luke's Hospital · USUniversity of Ferrara · IT

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Young Women With Acute Myocardial InfarctionR01HL081153 · NHLBI · YALE UNIVERSITY · PI KRUMHOLZ, HARLAN MARC · 2007 to 2012
$10.6M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL081153
6 · The paper itself

Abstract

introductionDespite evidence supporting the benefits of marriage on cardiovascular health, the impact of marital/partner status on the long-term readmission of young acute myocardial infarction (AMI) survivors is less clear. We examined the association between marital/partner status and 1-year all-cause readmission and explored sex differences among young AMI survivors.

methodsData were from the VIRGO study (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients), which enrolled young adults aged 18-55 years with AMI (2008-2012). The primary end point was all-cause readmission within 1 year of hospital discharge, obtained from medical records and patient interviews and adjudicated by a physician panel. We performed Cox proportional hazards models with sequential adjustment for demographic, socioeconomic, clinical, and psychosocial factors. Sex-marital/partner status interaction was also tested.

resultsOf the 2,979 adults with AMI (2002 women [67.2%]; mean age 48 [interquartile range, 44-52] years), unpartnered individuals were more likely to experience all-cause readmissions compared with married/partnered individuals within the first year after hospital discharge (34.6% versus 27.2%, hazard ratio [HR] = 1.31; 95% confidence interval [CI], 1.15-1.49). The association attenuated but remained significant after adjustment for demographic and socioeconomic factors (adjusted HR, 1.16; 95% CI, 1.01-1.34), and it was not significant after further adjusting for clinical factors and psychosocial factors (adjusted HR, 1.10; 95%CI, 0.94-1.28). A sex-marital/partner status interaction was not significant (p = 0.69). Sensitivity analysis using data with multiple imputation and restricting outcomes to cardiac readmission yielded comparable results.

conclusionsIn a cohort of young adults aged 18-55 years, unpartnered status was associated with 1.3-fold increased risk of all-cause readmission within 1 year of AMI discharge. Further adjustment for demographic, socioeconomic, clinical, and psychosocial factors attenuated the association, suggesting that these factors may explain disparities in readmission between married/partnered versus unpartnered young adults. Whereas young women experienced more readmission compared to similar-aged men, the association between marital/partner status and 1-year readmission did not vary by sex.

Indexed as

Myocardial InfarctionPatient ReadmissionFemaleHeartHumansMaleMiddle AgedRisk FactorsSocioeconomic FactorsYoung Adult

Identifiers

PMID38277368
PMCPMC10817183
OpenAlexW4391250718

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.