Evidence map›Paper›PMID 38277259›Full record

ArticleJournal of the American Chemical Society2024

High-Affinity Aptamers for

Obtin Alkhamis, Juan Canoura, Yuyang Wu, Nicole A Emmons, Yuting Wang, Kevin M Honeywell, Kevin W Plaxco, Tod E Kippin, Yi Xiao

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 52 citations in OpenAlex.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Reagentless Real-Time ATP Monitoring with New DNA Aptamers.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Obtin AlkhamisDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27607, United States.
Juan CanouraDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27607, United States.
Yuyang WuDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, United States.
Nicole A EmmonsDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, California 93106, United States.
Yuting WangDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, California 93106, United States.
Kevin M HoneywellDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, United States.
Kevin W PlaxcoDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, United States.
Tod E KippinDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, California 93106, United States.
Yi XiaoDepartment of Chemistry, North Carolina State University, Raleigh, North Carolina 27607, United States.ORCID 0000-0001-7278-9811
University of California, Santa Barbara · USNorth Carolina State University · US

Funding

Bio-electrochemical detectors for in vivo continuous monitoringR01EB022015 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI KIPPIN, TOD EDWARD, PLAXCO, KEVIN W · 2017 to 2025
$4.6M
Modular, in-situ probes of brain chemistryR01DA051100 · NIDA · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI KIPPIN, TOD EDWARD, PLAXCO, KEVIN W · 2020 to 2023
$2.1M
NIBIB NIH HHS R01 EB022015NIDA NIH HHS R01 DA051100
6 · The paper itself

Abstract

The ability to quantify cocaine in biological fluids is crucial for both the diagnosis of intoxication and overdose in the clinic as well as investigation of the drug's pharmacological and toxicological effects in the laboratory. To this end, we have performed high-stringency

Indexed as

Aptamers, NucleotideBiosensing TechniquesCocaineAnimalsHumansSerumAptamers, NucleotideCocaine

Identifiers

PMID38277259
PMCPMC11849797
OpenAlexW4391251246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.