Evidence map›Paper›PMID 38276695›Full record

ArticlePolymers2024

Polysaccharide Composite Alginate-Pectin Hydrogels as a Basis for Developing Wound Healing Materials.

Galina A Davydova, Leonid L Chaikov, Nikolay N Melnik, Radmir V Gainutdinov, Irina I Selezneva, Elena V Perevedentseva, Muhriddin T Mahamadiev, Vadim A Proskurin, Daniel S Yakovsky, Aurel George Mohan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Double-layer microencapsulation ofBiotechnology reports (Amsterdam, Netherlands) · 2026
    Article
  5. Review
  6. Poloxamer-based hydrogel with EGCG and rhEGF for diabetic foot ulcer treatment.Journal of materials science. Materials in medicine · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Galina A DavydovaFederal State Institution of Science Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences (ITEB RAS), Institutskaya St., 3, Pushchino 142290, Moscow Region, Russia.ORCID 0000-0003-4215-7084
Leonid L ChaikovFederal State Budgetary Institution of Science P.N. Lebedev Physical Institute, Russian Academy of Sciences, Leninsky Prospekt, 53, GSP-1, Moscow 119991, Russia.
Nikolay N MelnikFederal State Budgetary Institution of Science P.N. Lebedev Physical Institute, Russian Academy of Sciences, Leninsky Prospekt, 53, GSP-1, Moscow 119991, Russia.ORCID 0000-0002-7058-0333
Radmir V GainutdinovFederal Research Centre "Crystallography and Photonics" of the Russian Academy of Sciences, Leninsky Prospekt, 59, Moscow 119333, Russia.ORCID 0000-0002-5384-4026
Irina I SeleznevaFederal State Institution of Science Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences (ITEB RAS), Institutskaya St., 3, Pushchino 142290, Moscow Region, Russia.
Elena V PerevedentsevaFederal State Budgetary Institution of Science P.N. Lebedev Physical Institute, Russian Academy of Sciences, Leninsky Prospekt, 53, GSP-1, Moscow 119991, Russia.ORCID 0000-0002-1489-6747
Muhriddin T MahamadievFederal State Budgetary Institution of Science P.N. Lebedev Physical Institute, Russian Academy of Sciences, Leninsky Prospekt, 53, GSP-1, Moscow 119991, Russia.
Vadim A ProskurinPushchino Branch of Federal State Budgetary Educational Institution of Higher Education "Russian Biotechnology University (ROSBIOTECH)", Nauki Ave. 3, Pushchino 142290, Moscow Region, Russia.
Daniel S YakovskyDepartment of Biotechnology, Institute of Natural Science, Federal State Budgetary Educational Institution of Higher Education "Tula State University", Lenin Ave. 92, 9th Academic Building, Tula 300012, Russia.
Aurel George MohanFaculty of Medicine and Pharmacy, University of Oradea, 10 P-ta 1 December Street, 410073 Oradea, Romania.
Julietta V RauIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, Italy.ORCID 0000-0002-7953-1853
P.N. Lebedev Physical Institute of the Russian Academy of Sciences · RUInstitute of Theoretical and Experimental Biophysics · RURussian Academy of Sciences · RUSechenov University · RUTula State University · RUUniversity of Oradea · RO

Funding

State assignment of the Ministry of Science of the Russian Federation FFWU-2019-0001State assignment of the Ministry of Science of the Russian Federation N 075-01025-23-01
6 · The paper itself

Abstract

This article presents materials that highlight the bioengineering potential of polymeric systems of natural origin based on biodegradable polysaccharides, with applications in creating modern products for localized wound healing. Exploring the unique biological and physicochemical properties of polysaccharides offers a promising avenue for the atraumatic, controlled restoration of damaged tissues in extensive wounds. The study focused on alginate, pectin, and a hydrogel composed of their mixture in a 1:1 ratio. Atomic force microscopy data revealed that the two-component gel exhibits greater cohesion and is characterized by the presence of filament-like elements. The dynamic light scattering method indicated that this structural change results in a reduction in the damping of acoustic modes in the gel mixture compared to the component gels. Raman spectroscopy research on these gels revealed the emergence of new bonds between the components' molecules, contributing to the observed effects. The biocompatibility of the gels was evaluated using dental pulp stem cells, demonstrating that all the gels exhibit biocompatibility.

Indexed as

alginatedamaged tissuesgelshydrogelspectinpolysaccharideswound healing

Identifiers

PMID38276695
PMCPMC10819040
OpenAlexW4391110754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.