Evidence map›Paper›PMID 38276606›Full record

ArticleMolecules (Basel, Switzerland)2024

Anticancer Activity of Astaxanthin-Incorporated Chitosan Nanoparticles.

Eun Ju Hwang, Young-Il Jeong, Kyong-Je Lee, Young-Bob Yu, Seung-Ho Ohk, Sook-Young Lee

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Eun Ju HwangMarine Bio Research Center, Chosun University, Wando 59146, Jeonnam, Republic of Korea.
Young-Il JeongResearch Institute of Convergence of Biomedical Sciences, Pusan National University Yangsan Hospital, Yangsan 50612, Gyeongnam, Republic of Korea.ORCID 0000-0002-9832-4331
Kyong-Je LeeDepartment of Prosthodontics, Chosun University Dental Hospital, Gwangju 61452, Republic of Korea.
Young-Bob YuDepartment of Paramedicine, Nambu University, Gwangju 62271, Republic of Korea.ORCID 0000-0001-7785-5988
Seung-Ho OhkDepartment of Oral Microbiology, Chonnam National University School of Dentistry, Gwangju 61452, Republic of Korea.ORCID 0000-0001-9828-1143
Sook-Young LeeMarine Bio Research Center, Chosun University, Wando 59146, Jeonnam, Republic of Korea.ORCID 0000-0002-1944-1274
Chosun University · KRChonnam National University · KRChosun University Dental Hospital · KRNambu University · KRPusan National University Yangsan Hospital · KR

Funding

Korea Institute of Marine Science & Technology Promotion 20210656
6 · The paper itself

Abstract

Astaxanthin (AST)-encapsulated nanoparticles were fabricated using glycol chitosan (Chito) through electrostatic interaction (abbreviated as ChitoAST) to solve the aqueous solubility of astaxanthin and improve its biological activity. AST was dissolved in organic solvents and then mixed with chitosan solution, followed by a dialysis procedure. All formulations of ChitoAST nanoparticles showed small diameters (less than 400 nm) with monomodal distributions. Analysis with Fourier transform infrared (FT-IR) spectroscopy confirmed the specific peaks of AST and Chito. Furthermore, ChitoAST nanoparticles were formed through electrostatic interactions between Chito and AST. In addition, ChitoAST nanoparticles showed superior antioxidant activity, as good as AST itself; the half maximal radical scavenging concentrations (RC

Indexed as

ChitosanNanoparticlesAnimalsAntioxidantsMiceSpectroscopy, Fourier Transform InfraredXanthophyllsAntioxidantsastaxanthineChitosanXanthophyllsanticancerastaxanthinchitosannanoparticleROS scavenging

Identifiers

PMID38276606
PMCPMC10818874
OpenAlexW4391100317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.