Evidence map›Paper›PMID 38276583›Full record

ReviewMolecules (Basel, Switzerland)2024

On Water Arrangements in Right- and Left-Handed DNA Structures.

Liliya A Yatsunyk, Stephen Neidle

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liliya A YatsunykDepartment of Chemistry and Biochemistry, Swarthmore College, Swarthmore, PA 19081, USA.ORCID 0000-0003-3946-0939
Stephen NeidleUCL School of Pharmacy, University College London, London WC1N 1AX, UK.ORCID 0000-0003-0622-6548

Funding

Deciphering the structure and dynamics of non-canonical DNA implicated in cancerR15CA253134 · NCI · SWARTHMORE COLLEGE · PI YATSUNYK, LILIYA A · 2020 to 2020
$432k
NCI NIH HHS R15 CA253134
6 · The paper itself

Abstract

DNA requires hydration to maintain its structural integrity. Crystallographic analyses have enabled patterns of water arrangements to be visualized. We survey these water motifs in this review, focusing on left- and right-handed duplex and quadruplex DNAs, together with the i-motif. Common patterns of linear spines of water organization in grooves have been identified and are widely prevalent in right-handed duplexes and quadruplexes. By contrast, a left-handed quadruplex has a distinctive wheel of hydration populating the almost completely circular single groove in this structure.

Indexed as

DNA, Z-FormG-QuadruplexesChemical PhenomenaDNANucleic Acid ConformationWaterDNADNA, Z-FormWatercrystal structuresleft- and right-handed DNAsquadruplex DNAsspine of hydrationwater networkswheel of hydration

Identifiers

PMID38276583
PMCPMC10820154

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.