Evidence map›Paper›PMID 38276479›Full record

ArticlePharmaceutics2023

Synthesis, Characterization, and Investigation of Anti-Inflammatory and Cytotoxic Activities of Novel Thiourea Derivatives of Naproxen.

Nikola Nedeljković, Miloš Nikolić, Petar Čanović, Milan Zarić, Radica Živković Zarić, Jelena Bošković, Marina Vesović, Jovana Bradić, Marijana Anđić, Aleksandar Kočović and 4 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nikola NedeljkovićDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.ORCID 0000-0003-4560-2630
Miloš NikolićDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.ORCID 0000-0002-6960-3438
Petar ČanovićDepartment of Biochemistry, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Milan ZarićDepartment of Biochemistry, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.ORCID 0000-0001-7004-2239
Radica Živković ZarićDepartment of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Jelena BoškovićDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.ORCID 0000-0003-0768-3951
Marina VesovićDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Jovana BradićDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Marijana AnđićDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Aleksandar KočovićDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Marina NikolićCenter of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Vladimir JakovljevićCenter of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Svetozara Markovića 69, 34000 Kragujevac, Serbia.
Zorica VujićDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Vladimir DobričićDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.ORCID 0000-0002-5086-9017

Funding

Faculty of Medical Sciences, University of Kragujevac 11/20Ministry of Science, Technological Development and Innovation, Republic of Serbia 451-03-47/2023-01/200111Ministry of Science, Technological Development and Innovation, Republic of Serbia 451-03-47/2023-01/200161Science Fund of the Republic of Serbia 7739840
6 · The paper itself

Abstract

The objective of this study was to synthesize seven novel thiourea derivatives of naproxen (

Indexed as

5-LOXanti-inflammatory activityapoptosisCOX-2cytotoxic activityMTTnaproxenpaw edemathiourea

Identifiers

PMID38276479
PMCPMC10820527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.