ArticleSensors (Basel, Switzerland)2024
Characterization of Walking in Mild Parkinson's Disease: Reliability, Validity and Discriminant Ability of the Six-Minute Walk Test Instrumented with a Single Inertial Sensor.
Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07525973 (The Effect of Eye Exercises on Physical Function, Balance, and Fall Risk in Patients With Parkinson's Disease), which is not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Eye Exercises on Physical Function, Balance, and Fall Risk in Patients With Parkinson's Disease: A Randomized Controlled Trial
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Gait asymmetry in Parkinson's disease - a systematic review and meta-analysis (AsymmGait-Parkinson study).Scientific reports · 2026Pooled it
- The role of virtual reality in balance training for Parkinson's disease: a systematic review and meta-analysis.Frontiers in rehabilitation sciences · 2026Pooled it
- Effects of wearable devices on gait, balance, and motor function in people with Parkinson's disease: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Impact of Virtual Reality Alone and in Combination with Conventional Therapy on Balance in Parkinson's Disease: A Systematic Review with a Meta-Analysis of Randomized Controlled Trials.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Comparative Analysis of Support Vector Machine Variants for Human Activity Recognition Using Wearable Sensor Data.Sensors (Basel, Switzerland) · 2026Article
- Machine Learning in Adapted Physical Activity: Clinical Applications, Monitoring, and Implementation Pathways for Personalized Exercise in Chronic Conditions: A Narrative Review.Journal of functional morphology and kinesiology · 2026Review
- Gait dysfunction as an early marker of phenoconversion in REM sleep behavior disorder.Scientific reports · 2026Article
- Six-minute walk test instrumented with a single inertial sensor: dataset from healthy adults of different ages.Scientific data · 2026Article
- New gait performance indices and cognitive functions: a longitudinal pre-post follow-up after rehabilitation in people with Parkinson's disease.Frontiers in human neuroscience · 2026Article
- Walking Capacity in Parkinson's Disease: Test-Retest Reliability of the 6-min Walk Test on a Non-Linear Circuit.Healthcare (Basel, Switzerland) · 2025Article
- Assessing the Validity and Reliability of a Single Lumbar-Mounted IMU System for Gait Analysis.Sensors (Basel, Switzerland) · 2025Article
- Assessment of reliability and concurrent validity of a single trunk-based IMU system to quantify spatiotemporal parameters in healthy individuals.BMC sports science, medicine & rehabilitation · 2025Article
- Comparing the Informative Value of 2-Minute Segments of the 6-Minute Walk Test: Insights into a Prospective Study on Parkinson's Disease.Sensors (Basel, Switzerland) · 2025Article
- Hierarchical clustering approach to movement smoothness and temporal adaptation in rhythmic step aerobics training in middle aged women.Scientific reports · 2025Article
- REM density in Parkinson's disease: association with motor, cognitive, autonomic function, and dopaminergic medication.NPJ Parkinson's disease · 2025Article
- Using machine learning to identify Parkinson's disease severity subtypes with multimodal data.Journal of neuroengineering and rehabilitation · 2025Article
- New gait performance indices and cognitive functions: a pilot study on correlation in people with Parkinson's disease.Frontiers in human neuroscience · 2025Article
- Social support may not impact physical function outcomes following a tango or walking intervention in people with Parkinson's disease: an exploratory analysis of a randomized controlled trial.Frontiers in psychology · 2025Article
- Machine Learning and Statistical Analyses of Sensor Data Reveal Variability Between Repeated Trials in Parkinson's Disease Mobility Assessments.Sensors (Basel, Switzerland) · 2024Article
- The Role of the Six-Minute Walk Test in the Functional Evaluation of the Efficacy of Rehabilitation Programs After COVID-19.Life (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Although the 6-Minute Walk Test (6MWT) is among the recommended clinical tools to assess gait impairments in individuals with Parkinson's disease (PD), its standard clinical outcome consists only of the distance walked in 6 min. Integrating a single Inertial Measurement Unit (IMU) could provide additional quantitative and objective information about gait quality complementing standard clinical outcome. This study aims to evaluate the test-retest reliability, validity and discriminant ability of gait parameters obtained by a single IMU during the 6MWT in subjects with mild PD. Twenty-two people with mild PD and ten healthy persons performed the 6MWT wearing an IMU placed on the lower trunk. Features belonging to rhythm and pace, variability, regularity, jerkiness, intensity, dynamic instability and symmetry domains were computed. Test-retest reliability was evaluated through the Intraclass Correlation Coefficient (ICC), while concurrent validity was determined by Spearman's coefficient. Mann-Whitney U test and the Area Under the receiver operating characteristic Curve (AUC) were then applied to assess the discriminant ability of reliable and valid parameters. Results showed an overall high reliability (ICC ≥ 0.75) and multiple significant correlations with clinical scales in all domains. Several features exhibited significant alterations compared to healthy controls. Our findings suggested that the 6MWT instrumented with a single IMU can provide reliable and valid information about gait features in individuals with PD. This offers objective details about gait quality and the possibility of being integrated into clinical evaluations to better define walking rehabilitation strategies in a quick and easy way.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.