Evidence map›Paper›PMID 38276287›Full record

ArticleLife (Basel, Switzerland)2024

Survival Trends in Pediatric Differentiated Thyroid Cancer: A Middle Eastern Perspective.

Akram Al-Ibraheem, Mohamed Al-Shammaa, Ahmed Saad Abdlkadir, Feras Istatieh, Ula Al-Rasheed, Thomas Pascual, Rawad Rihani, Hadeel Halalsheh, Taleb Ismael, Aysar Khalaf and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Nuclear Medicine in IRAQ: From a Pioneering Past to Future Progress.Journal of multidisciplinary healthcare · 2026
    Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Akram Al-IbraheemDepartment of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.ORCID 0000-0002-0978-4716
Mohamed Al-ShammaaDepartment of Nuclear Medicine, Radiotherapy and Nuclear Medicine Hospital, Bab Al-Muadham, Baghdad 10047, Iraq.
Ahmed Saad AbdlkadirDepartment of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.ORCID 0000-0002-2009-5110
Feras IstatiehDepartment of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.
Ula Al-RasheedDepartment of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.
Thomas PascualPhilippine Nuclear Research Institute, Department of Science and Technology, Quezon City 1101, Philippines.
Rawad RihaniDepartment of Pediatrics, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.
Hadeel HalalshehDepartment of Pediatrics, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.ORCID 0000-0003-4803-1976
Taleb IsmaelDepartment of Pediatrics, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.
Aysar KhalafDepartment of Nuclear Medicine, Warith International Cancer Institute, Karbala 56001, Iraq.
Iyad SultanDepartment of Pediatrics, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.ORCID 0000-0002-2664-1565
Issa MohamadDepartment of Radiation Oncology, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.ORCID 0000-0003-0153-9131
Hikmat Abdel-RazeqDepartment of Medicine, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.ORCID 0000-0003-2833-6051
Asem MansourDepartment of Diagnostic Radiology, King Hussein Cancer Center (KHCC), Al-Jubeiha, Amman 11941, Jordan.
King Hussein Cancer Center · JOBaghdad Medical City · IQUniversity of Jordan · JOUniversity of Kerbala · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric Differentiated Thyroid Cancer (pedDTC) is a rare pediatric malignancy with an increasing incidence over time. To date, there is a paucity of literature specifically addressing pedDTC within the context of Middle Eastern ethnicity. This retrospective study aimed to assess the risk-stratifying factors for overall survival (OS) and event-free survival (EFS) in pediatric DTC patients from Iraq and Jordan. The medical records of 81 patients from two tertiary cancer institutes were retrieved. Kaplan-Meier analysis was employed to investigate OS and EFS, and the Cox proportional hazards model was employed to estimate hazard ratios. All patients underwent surgery and radioactive iodine therapy, with a median age of 14 and an interquartile range of 12-15. Lymph node involvement was observed in 55% of cases, while distant metastases were present in 13.5%. After a median follow-up period of 68 months, the 10-year survival rate was determined to be 94%, while the 10-year EFS rate was 58%. EFS was negatively impacted by cervical lymph node metastases and early age of diagnosis (

Indexed as

childrendistant metastasisevent-free survivallymph node metastasisMiddle Easternpediatric thyroid cancer

Identifiers

PMID38276287
PMCPMC10820815
OpenAlexW4391103304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.