Evidence map›Paper›PMID 38276241›Full record

ReviewJournal of personalized medicine2024

Vitamin D-The Iceberg in Endometriosis-Review and Meta-Analysis.

Alexandra Ursache, Ludmila Lozneanu, Iuliana Elena Bujor, Cristina Elena Mandici, Lucian Vasile Boiculese, Alexandra Irma Gabriela Bausic, Mihaela Grigore, Demetra Socolov, Daniela Roxana Matasariu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alexandra UrsacheDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.ORCID 0000-0002-8207-7655
Ludmila LozneanuDepartment of Morpho-Functional Sciences I-Histology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.ORCID 0000-0002-3994-6579
Iuliana Elena BujorDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.
Cristina Elena MandiciDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.
Lucian Vasile BoiculeseBiostatistics, Department of Preventive Medicine and Interdisciplinarity, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.ORCID 0000-0001-5825-6189
Alexandra Irma Gabriela BausicDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Carol Davila', 020021 Bucharest, Romania.ORCID 0000-0001-7764-7839
Mihaela GrigoreDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.
Demetra SocolovDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.
Daniela Roxana MatasariuDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.ORCID 0000-0002-2862-2069
Grigore T. Popa University of Medicine and Pharmacy · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Although vitamin D has many known biological effects, very little research has been conducted on how vitamin D may be related or play a role in endometriosis. The aim of our study was to perform an evaluation regarding vitamin D levels and possible implications in endometriosis through a statistical analysis of the data collected from the included studies. (2) Methods: For this review, we searched the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, and PubMed/Internet portal of the National Library of Medicine databases using several keywords related to our topic. (3) Results: Only nine articles were identified as complete or possessing the capacity to compute all available data. We totalized a number of 976 patients with endometriosis and 674 controls. From the nine studies included in our analysis, three of them claim there is no difference between women with and without endometriosis concerning 25(OH) vitamin D levels; however, the other six studies found significant differences regarding this aspect. (4) Conclusions: Our results underscored the complexity of analyzing the role of the vitamin D complex in a challenging condition like endometriosis and suggest that focusing on the tissue level might be essential to obtain accurate answers to our inquiries.

Indexed as

1,25(OH)2D31,25(OH)D25(OH)D25(OH)D3biomarkerELISAendometriosisvitamin Dvitamin D binding proteinvitamin D receptor

Identifiers

PMID38276241
PMCPMC10821152
OpenAlexW4391105412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.