Evidence map›Paper›PMID 38276220›Full record

ReviewJournal of personalized medicine2023

Current Management and Future Directions for Pulmonary Arterial Hypertension Associated with Congenital Heart Disease.

Ahmed K Mahmoud, Mohammed Tiseer Abbas, Moaz A Kamel, Juan M Farina, Milagros Pereyra, Isabel G Scalia, Timothy Barry, Chieh-Ju Chao, Francois Marcotte, Chadi Ayoub and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Ahmed K MahmoudDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
Mohammed Tiseer AbbasDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0009-0004-7212-435X
Moaz A KamelDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
Juan M FarinaDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0002-5824-8485
Milagros PereyraDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0003-4695-8436
Isabel G ScaliaDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0002-6459-9767
Timothy BarryDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0002-0576-2990
Chieh-Ju ChaoDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Francois MarcotteDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
Chadi AyoubDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
Robert L ScottDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
David S MajdalanyDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0002-5472-6689
Reza ArsanjaniDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.ORCID 0000-0001-7081-4286
WinnMed · USMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current management of patients with congenital heart disease has increased their survival into adulthood. This is accompanied by potential cardiac complications, including pulmonary hypertension associated with congenital heart disease (PAH-CHD). PAH-CHD constitutes a challenging subgroup of pulmonary hypertension and requires expert management to improve quality of life and prognosis. Novel agents have shown a significant improvement in morbidity and mortality in patients with pulmonary arterial hypertension. However, the long-term effects of these medications on PAH-CHD patients remain somewhat uncertain, necessitating treatment plans largely founded on the clinical experience of the healthcare providers. The aim of this review is to summarize the current evidence and future perspectives regarding treatment strategies for PAH-CHD to help better guide management of this complex disease.

Indexed as

bosentancongenital heart diseaseepoprostenolmacitentanongoing trialspulmonary hypertensionselexipagsildenafilsotatercept

Identifiers

PMID38276220
PMCPMC10817644
OpenAlexW4389991867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.