Evidence map›Paper›PMID 38276213›Full record

ArticleMicroorganisms2024

Metagenomic Characterisation of the Gut Microbiome and Effect of Complementary Feeding on

Kimberley Parkin, Debra J Palmer, Valerie Verhasselt, Nelly Amenyogbe, Matthew N Cooper, Claus T Christophersen, Susan L Prescott, Desiree Silva, David Martino

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. The Gut Microbiota of Peruvian Children Under the Age of Two During the Complementary Feeding Period.International journal of environmental research and public health · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kimberley ParkinTelethon Kids Institute, University of Western Australia, Nedlands, Perth, WA 6009, Australia.ORCID 0000-0002-7657-214X
Debra J PalmerTelethon Kids Institute, University of Western Australia, Nedlands, Perth, WA 6009, Australia.ORCID 0000-0003-2498-8343
Valerie VerhasseltTelethon Kids Institute, University of Western Australia, Nedlands, Perth, WA 6009, Australia.ORCID 0000-0002-5732-9048
Nelly AmenyogbeTelethon Kids Institute, University of Western Australia, Nedlands, Perth, WA 6009, Australia.
Matthew N CooperTelethon Kids Institute, University of Western Australia, Nedlands, Perth, WA 6009, Australia.
Claus T ChristophersenSchool of Molecular Life Sciences, Curtin University, Bentley, Perth, WA 6102, Australia.ORCID 0000-0003-1591-5871
Susan L PrescottMedical School, University of Western Australia, Nedlands, Perth, WA 6009, Australia.ORCID 0000-0003-4845-8590
Desiree SilvaMedical School, University of Western Australia, Nedlands, Perth, WA 6009, Australia.ORCID 0000-0003-4454-466X
David MartinoTelethon Kids Institute, University of Western Australia, Nedlands, Perth, WA 6009, Australia.ORCID 0000-0001-6823-4696
The Kids Research Institute Australia · AUEdith Cowan University · AUUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complementary feeding induces dramatic ecological shifts in the infant gut microbiota toward more diverse compositions and functional metabolic capacities, with potential implications for immune and metabolic health. The aim of this study was to examine whether the age at which solid foods are introduced differentially affects the microbiota in predominantly breastfed infants compared with predominantly formula-fed infants. We performed whole-genome shotgun metagenomic sequencing of infant stool samples from a cohort of six-month-old Australian infants enrolled in a nested study within the ORIGINS Project longitudinal birth cohort. Infants born preterm or those who had been administered antibiotics since birth were excluded. The taxonomic composition was highly variable among individuals at this age. Predominantly formula-fed infants exhibited a higher microbiome diversity than predominantly breastfed infants. Among the predominantly breastfed infants, the introduction of solid foods prior to five months of age was associated with higher alpha diversity than solid food introduction after six months of age, primarily due to the loss of

Indexed as

Bifidobacteriumbreastfeedingcomplementary feedinggut microbiomeshotgun metagenomicsthe ORIGINS project

Identifiers

PMID38276213
PMCPMC10819277
OpenAlexW4391110960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.