Evidence map›Paper›PMID 38276081›Full record

ReviewJournal of clinical medicine2024

Comparison of Combined Parenteral and Oral Hormonal Contraceptives: A Systematic Review and Meta-Analysis of Randomized Trials.

Gábor Vleskó, Fanni Adél Meznerics, Péter Hegyi, Brigitta Teutsch, Márkó Unicsovics, Zoltán Sipos, Péter Fehérvári, Nándor Ács, Szabolcs Várbíró, Márton Keszthelyi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gábor VleskóDepartment of Obstetrics and Gynecology, Semmelweis University, 1082 Budapest, Hungary.
Fanni Adél MeznericsCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Brigitta TeutschCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Márkó UnicsovicsDepartment of Obstetrics and Gynecology, Semmelweis University, 1082 Budapest, Hungary.
Zoltán SiposInstitute for Translational Medicine, Medical School, University of Pécs, 7621 Pécs, Hungary.
Péter FehérváriCentre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Nándor ÁcsDepartment of Obstetrics and Gynecology, Semmelweis University, 1082 Budapest, Hungary.
Szabolcs VárbíróDepartment of Obstetrics and Gynecology, Semmelweis University, 1082 Budapest, Hungary.
Márton KeszthelyiDepartment of Obstetrics and Gynecology, Semmelweis University, 1082 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelivering contraceptive hormones through a transdermal patch or a vaginal ring might have advantages over the traditional oral route.

objectivesTo compare the effectiveness, compliance, and side effect profile of oral and parenteral drug administration methods.

methodsWe performed a systematic literature search in four medical databases-MEDLINE (via PubMed), Cochrane Library (CENTRAL), Embase, and Scopus-from inception to 20 November 2022. Randomized controlled trials assessing the efficacy, compliance, and adverse event profile of combined parenteral and oral hormonal contraceptives were included.

resultsOur systematic search provided 3952 records; after duplicate removal, we screened 2707 duplicate-free records. A total of 13 eligible studies were identified after title, abstract, and full-text selection. We observed no significant difference in contraceptive efficacy (Pearl Index) between oral and parenteral drug administration (MD = -0.06, CI: -0.66-0.53; I

conclusionBoth parenteral and oral contraceptives can be used as an effective contraceptive method, and the route of administration should be tailored to patient needs and adverse event occurrence.

Indexed as

combined oral contraceptioncombined parenteral contraceptioncontraceptive patchhormonal contraceptionvaginal ring

Identifiers

PMID38276081
PMCPMC10816843

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.