ArticleViruses2024
The Global Evolutionary History of Orf Virus in Sheep and Goats Revealed by Whole Genomes Data.
Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Host-Orf virus interactions: A comprehensive review of pathogenesis and immune evasion mechanisms.Virulence · 2026Review
- Isolation and whole-genome characterization of an Orf virus strain from a goat in Binzhou, Shandong Province, China.Archives of virology · 2026Article
- Genomic characterization of the first goat-associated orf virus genome sequenced directly from a human clinical sample in Portugal.Archives of virology · 2026Article
- Molecular Characterisation of Orf Virus in Goats From Eastern Türkiye.Veterinary medicine and science · 2026Article
- First identification of orf virus from an outbreak of contagious ecthyma in Polish sheep.Journal of veterinary research · 2026Article
- Molecular Detection and Characterization of Orf Virus in Goats With Clinical Signs From Four Districts of Tanzania.Veterinary medicine and science · 2026Article
- Unravelling the Evolutionary Complexity of Orf Virus: A Global and Multi-Host Perspective.Viruses · 2026Article
- The whole genome analysis of four Orf virus strains from Europe and South America.Virus evolution · 2026Article
- Development and application of a novel indirect ELISA based on recombinant ORFV114 protein for serodiagnosis of Orf virus in goats.Veterinary research communications · 2025Article
- Contagious ecthyma in small ruminants: from etiology to vaccine challenges - a review.Veterinary research communications · 2025Review
- Article
- The identification and genetic characteristics of the Orf virus strain (ORFV-CL24) isolated from Jilin province, China.Frontiers in microbiology · 2025Article
- Retrospective research: identifying and conducting phylogenetic analyses on four Orf virus strains isolated in Yunnan province between 2021 and 2023-revealing their significance and characteristic features.Frontiers in veterinary science · 2024Article
Corrections and comments
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Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
Abstract
Orf virus (ORFV) belongs to the genus Parapoxvirus (Poxviridae family). It is the causative agent of contagious ecthyma (CE) that is an economically detrimental disease affecting small ruminants globally. Contagious ecthyma outbreaks are usually reported in intensive breeding of sheep and goats but they have also been reported in wildlife species. Notably, ORFV can infect humans, leading to a zoonotic disease. This study aims to elucidate the global evolutionary history of ORFV genomes in sheep and goats, including the first genomes from Central America in the analyses. In comparison to the last study on ORFV whole genomes, the database now includes 11 more sheep and goat genomes, representing an increase of 42%. The analysis of such a broader database made it possible to obtain a fine molecular dating of the coalescent time for ORFV S and G genomes, further highlighting the genetic structuring between sheep and goat genomes and corroborating their emergence in the latter half of 20th century.
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