Evidence map›Paper›PMID 38275943›Full record

ArticleViruses2023

Development of a Replication-Deficient Bacteriophage Reporter Lacking an Essential Baseplate Wedge Subunit.

Jose Gil, John Paulson, Henriett Zahn, Matthew Brown, Minh M Nguyen, Stephen Erickson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jose GilLaboratory Corporation of America Holdings, Los Angeles, CA 90062, USA.
John PaulsonLaboratory Corporation of America Holdings, New Brighton, MN 55112, USA.ORCID 0000-0002-4263-7283
Henriett ZahnLaboratory Corporation of America Holdings, New Brighton, MN 55112, USA.
Matthew BrownLaboratory Corporation of America Holdings, Burlington, NC 27215, USA.
Minh M NguyenLaboratory Corporation of America Holdings, New Brighton, MN 55112, USA.
Stephen EricksonLaboratory Corporation of America Holdings, New Brighton, MN 55112, USA.ORCID 0000-0002-4024-7783
LabCorp (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Engineered bacteriophages (phages) can be effective diagnostic reporters for detecting a variety of bacterial pathogens. Although a promising biotechnology, the large-scale use of these reporters may result in the unintentional release of genetically modified viruses. In order to limit the potential environmental impact, the ability of these phages to propagate outside the laboratory was targeted. The phage SEA1 has been previously engineered to facilitate food safety as an accurate and sensitive reporter for

Indexed as

BacteriophagesBacteriaSalmonellabacteriophagebaseplate wedge subunitluciferase reporter phagephage-based detectionreplication-deficient phageSalmonella entericasynthetic phage

Identifiers

PMID38275943
PMCPMC10821221
OpenAlexW4390007128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.