Evidence map›Paper›PMID 38275828›Full record

GuidelineCurrent oncology (Toronto, Ont.)2023

Management of Uveal Melanoma: Updated Cancer Care Alberta Clinical Practice Guideline.

Ezekiel Weis, Brae Surgeoner, Thomas G Salopek, Tina Cheng, Martin Hyrcza, Xanthoula Kostaras, Matthew Larocque, Greg McKinnon, John McWhae, Geetha Menon and 4 more

Open access · goldAbstract readReviewGuideline
In one paragraph

Guideline in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Intensive Surveillance and Aggressive Multimodal Treatment for Liver Metastases From Uveal Melanoma.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Ezekiel WeisDepartment of Ophthalmology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Brae SurgeonerCancer Care Alberta, Calgary, AB T2S 3C3, Canada.
Thomas G SalopekDivision of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Tina ChengTom Baker Cancer Center, Division of Medical Oncology, Department of Oncology, Calgary, AB T2N 4N2, Canada.
Martin HyrczaLaboratory Medicine, Department of Pathology, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB T2N 1N4, Canada.
Xanthoula KostarasCancer Care Alberta, Calgary, AB T2S 3C3, Canada.
Matthew LarocqueDivision of Medical Physics, Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 1Z2, Canada.
Greg McKinnonDivision of Surgical Oncology, University of Calgary, Calgary, AB T2N 1N4, Canada.
John McWhaeDepartments of Surgery and Oncology, University of Calgary, Calgary, AB T2N 1N4, Canada.
Geetha MenonDivision of Medical Physics, Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 1Z2, Canada.ORCID 0000-0002-4718-907X
Jose MonzonTom Baker Cancer Center, Division of Medical Oncology, Department of Oncology, Calgary, AB T2N 4N2, Canada.
Albert D MurthaDivision of Radiation Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB T6G 1Z2, Canada.
John WalkerDivision of Medical Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB T6G 1Z2, Canada.
Claire Temple-OberleDivision of Surgical Oncology, University of Calgary, Calgary, AB T2N 1N4, Canada.
University of Alberta · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this guideline update is to reassess and update recommendations in the prior guideline from 2016 on the appropriate management of patients with uveal melanoma.

methodsIn 2021, a multidisciplinary working group from the Provincial Cutaneous Tumour Team, Cancer Care Alberta, Alberta Health Services was convened to update the guideline. A comprehensive review of new research evidence in PubMed as well as new clinical practice guidelines from prominent oncology groups informed the update. An enhancement in methodology included adding levels of evidence and strength of recommendations. The updated guideline was circulated to all members of the Provincial Cutaneous Tumour Team for review and endorsement.

resultsNew and modified recommendations address provider training requirements, diagnostic imaging for the detection of metastases, neo-adjuvant pre-enucleation radiotherapy, intravitreal anti-vascular endothelial growth factor agents for radiation retinopathy, genetic prognostic testing, surveillance following definitive local therapy, and systemic therapy for patients with metastatic uveal melanoma. DISCUSSION: The recommendations represent evidence-based standards of care agreed to by a large multidisciplinary group of healthcare professionals.

Indexed as

MelanomaSkin NeoplasmsUveal NeoplasmsAlbertaHumansUveal Melanomachoroidal melanomairis melanomamelanomaocular melanomaophthalmologypractice guidelinesuveal melanoma

Identifiers

PMID38275828
PMCPMC10814960
OpenAlexW4389993802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.