Evidence map›Paper›PMID 38275667›Full record

ReviewCurrent issues in molecular biology2023

Insights into the Effects of Hydroxycinnamic Acid and Its Secondary Metabolites as Antioxidants for Oxidative Stress and Plant Growth under Environmental Stresses.

Sindiswa Khawula, Arun Gokul, Lee-Ann Niekerk, Gerhard Basson, Marshall Keyster, Mihlali Badiwe, Ashwil Klein, Mbukeni Nkomo

Open access · goldAbstract readReview
In one paragraph

Review in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Bioactive Compounds of Aboveground OrgansMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Whole-Cell Fungal Biotransformation ofMolecules (Basel, Switzerland) · 2026
    Article
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  18. The phenology ofFrontiers in pharmacology · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sindiswa KhawulaPlant Biotechnology Laboratory, Department of Agriculture, University of Zululand, Main Road, Kwa-Dlangezwa 3886, South Africa.
Arun GokulDepartment of Plant Sciences, Qwaqwa Campus, University of Free State, Phuthadithaba 9866, South Africa.ORCID 0000-0003-1575-0632
Lee-Ann NiekerkEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.
Gerhard BassonEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0001-9654-7681
Marshall KeysterEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-8718-736X
Mihlali BadiweDepartment of Plant Pathology, Stellenbosch University, Stellenbosch 7435, South Africa.ORCID 0000-0003-0876-9431
Ashwil KleinPlant Omics Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-5606-886X
Mbukeni NkomoPlant Biotechnology Laboratory, Department of Agriculture, University of Zululand, Main Road, Kwa-Dlangezwa 3886, South Africa.
University of the Western Cape · ZAUniversity of Zululand · ZAStellenbosch University · ZAUniversity of the Free State · ZA

Funding

National Research Foundation BAAP2204082813,129493,107023, 115280, 116346 and 109083
6 · The paper itself

Abstract

Plant immobility renders plants constantly susceptible to various abiotic and biotic stresses. Abiotic and biotic stresses are known to produce reactive oxygen species (ROS), which cause comparable cellular secondary reactions (osmotic or oxidative stress), leading to agricultural productivity constraints worldwide. To mitigate the challenges caused by these stresses, plants have evolved a variety of adaptive strategies. Phenolic acids form a key component of these strategies, as they are predominantly known to be secreted by plants in response to abiotic or biotic stresses. Phenolic acids can be divided into different subclasses based on their chemical structures, such as hydroxybenzoic acids and hydroxycinnamic acids. This review analyzes hydroxycinnamic acids and their derivatives as they increase under stressful conditions, so to withstand environmental stresses they regulate physiological processes through acting as signaling molecules that regulate gene expression and biochemical pathways. The mechanism of action used by hydroxycinnamic acid involves minimization of oxidative damage to maintain cellular homeostasis and protect vital cellular components from harm. The purpose of this review is to highlight the potential of hydroxycinnamic acid metabolites/derivatives as potential antioxidants. We review the uses of different secondary metabolites associated with hydroxycinnamic acid and their contributions to plant growth and development.

Indexed as

environmental stresseshydroxycinnamic acidhydroxycinnamic acid derivatives

Identifiers

PMID38275667
PMCPMC10814621
OpenAlexW4390048600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.