Evidence map›Paper›PMID 38275626›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Ameliorative Effects of Cumin Extract-Encapsulated Chitosan Nanoparticles on Skeletal Muscle Atrophy and Grip Strength in Streptozotocin-Induced Diabetic Rats.

Yu-Chiuan Wu, Min-Chien Su, Chun-Shien Wu, Pin-Yu Chen, I-Fen Chen, Feng-Huei Lin, Shyh-Ming Kuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yu-Chiuan WuRepublic of China Military Academy, Kaohsiung 830208, Taiwan.
Min-Chien SuDepartment of Biomedical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
Chun-Shien WuCenter of General Education, I-Shou University, Kaohsiung 84001, Taiwan.
Pin-Yu ChenDepartment of Biomedical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
I-Fen ChenDepartment of Biomedical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
Feng-Huei LinDepartment of Biomedical Engineering, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0002-2994-6671
Shyh-Ming KuoDepartment of Biomedical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
I-Shou University · TWNational Taiwan University · TWR.O.C Military Academy · TW

Funding

Ministry of Science and Technology Taiwan 109-2314-B-214-001-MY3, 111-2813-C-214-024-E
6 · The paper itself

Abstract

Skeletal muscle atrophy is a disorder characterized by reductions in muscle size and strength. Cumin extract (CE) possesses anti-inflammatory, antioxidant, and hypoglycemic properties. Its pharmaceutical applications are hindered by its low water solubility and by its cytotoxicity when administered at high doses. In this study, we have developed a simplified water distillation method using a rotary evaporator to isolate the active components in cumin seeds. The anti-inflammatory effects of CE and its potential to ameliorate skeletal muscle atrophy in rats with streptozotocin (STZ)-induced diabetes were evaluated. The half-maximal inhibitory concentration (IC

Indexed as

antioxidantchitosan nanoparticlescumindiabeticmuscle atrophy

Identifiers

PMID38275626
PMCPMC10812640
OpenAlexW4389975651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.