Evidence map›Paper›PMID 38275597›Full record

ReviewGenes2023

Hotspot Regions of Quantitative Trait Loci and Candidate Genes for Ear-Related Traits in Maize: A Literature Review.

Xingjie Zhang, Jiachen Sun, Yudong Zhang, Jinfeng Li, Meichen Liu, Linzhuo Li, Shaoxiong Li, Tingzhao Wang, Ranjan Kumar Shaw, Fuyan Jiang and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  6. Identification of hypophosphatasia in adults with persistent hypophosphatasemia: clinical-genetic characterization and a validated diagnostic tool.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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  13. Haplotype analysis and molecular marker development for the cold tolerance gene OsCTS11 at the seedling stage of rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  14. Plants (Basel, Switzerland) · 2025
    Article
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  17. Genetic architecture of key traits forHorticulture research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xingjie ZhangSchool of Agriculture, Yunnan University, Kunming 650500, China.
Jiachen SunCollege of Agronomy and Biotechnology, Yunnan Agricultural University, Kunming 650201, China.
Yudong ZhangInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming 650205, China.
Jinfeng LiSchool of Agriculture, Yunnan University, Kunming 650500, China.
Meichen LiuSchool of Agriculture, Yunnan University, Kunming 650500, China.
Linzhuo LiSchool of Agriculture, Yunnan University, Kunming 650500, China.
Shaoxiong LiSchool of Agriculture, Yunnan University, Kunming 650500, China.
Tingzhao WangCollege of Agronomy and Biotechnology, Yunnan Agricultural University, Kunming 650201, China.
Ranjan Kumar ShawInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming 650205, China.
Fuyan JiangInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming 650205, China.
Xingming FanInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming 650205, China.ORCID 0009-0009-4742-9246
Yunnan University · CNYunnan Academy of Agricultural Sciences · CNYunnan Agricultural University · CN

Funding

The National Natural, the Technology Talent and Platform Program 202205AF150028
6 · The paper itself

Abstract

In this study, hotspot regions, QTL clusters, and candidate genes for eight ear-related traits of maize (ear length, ear diameter, kernel row number, kernel number per row, kernel length, kernel width, kernel thickness, and 100-kernel weight) were summarized and analyzed over the past three decades. This review aims to (1) comprehensively summarize and analyze previous studies on QTLs associated with these eight ear-related traits and identify hotspot bin regions located on maize chromosomes and key candidate genes associated with the ear-related traits and (2) compile major and stable QTLs and QTL clusters from various mapping populations and mapping methods and techniques providing valuable insights for fine mapping, gene cloning, and breeding for high-yield and high-quality maize. Previous research has demonstrated that QTLs for ear-related traits are distributed across all ten chromosomes in maize, and the phenotypic variation explained by a single QTL ranged from 0.40% to 36.76%. In total, 23 QTL hotspot bins for ear-related traits were identified across all ten chromosomes. The most prominent hotspot region is bin 4.08 on chromosome 4 with 15 QTLs related to eight ear-related traits. Additionally, this study identified 48 candidate genes associated with ear-related traits. Out of these, five have been cloned and validated, while twenty-eight candidate genes located in the QTL hotspots were defined by this study. This review offers a deeper understanding of the advancements in QTL mapping and the identification of key candidates associated with eight ear-related traits. These insights will undoubtedly assist maize breeders in formulating strategies to develop higher-yield maize varieties, contributing to global food security.

Indexed as

Quantitative Trait LociZea maysChromosome MappingPhenotypePlant Breedingcandidate geneconsistent QTLear-related traitshotspot regionmaizequantitative trait loci

Identifiers

PMID38275597
PMCPMC10815758
OpenAlexW4390053254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.