Evidence map›Paper›PMID 38275565›Full record

ArticleDiseases (Basel, Switzerland)2023

Assessment of Gastrointestinal Adverse Effects during the First Six Months of "Biktarvy" Antiretroviral Therapy: Age-Related Patterns and Their Relation with Changes of 5 kg Weight Loss/Gain in the Initial Treatment Period.

Madalina-Ianca Suba, Simona-Alina Abu-Awwad, Ovidiu Rosca, Mirela-Mădălina Turaiche, Bogdan Hogea, Ahmed Abu-Awwad, Razvan Nitu, Voichita Elena Lazureanu

Open access · goldAbstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Madalina-Ianca SubaDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.
Simona-Alina Abu-AwwadDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0009-0003-6793-5361
Ovidiu RoscaDepartment XIII, Discipline of Infectious Diseases, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania.ORCID 0000-0001-8236-2205
Mirela-Mădălina TuraicheMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania.
Bogdan Hogea"Pius Brinzeu" Emergency Clinical County Hospital, Bld Liviu Rebreanu, No. 156, 300723 Timisoara, Romania.ORCID 0000-0003-4924-7832
Ahmed Abu-Awwad"Pius Brinzeu" Emergency Clinical County Hospital, Bld Liviu Rebreanu, No. 156, 300723 Timisoara, Romania.ORCID 0000-0002-6185-0960
Razvan Nitu"Pius Brinzeu" Emergency Clinical County Hospital, Bld Liviu Rebreanu, No. 156, 300723 Timisoara, Romania.
Voichita Elena LazureanuDepartment XIII, Discipline of Infectious Diseases, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania.
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe battle against HIV has led to the development of antiretroviral therapy (ART), including BIKTARVY MATERIALS AND

methodsThis retrospective cohort study, conducted over four years in Romania, examined 222 patients initiated on BIKTARVY

resultsThis study revealed significant differences in the prevalence of gastrointestinal symptoms between age groups, with older patients experiencing more symptoms. Notably, diarrhea did not exhibit a statistically significant age-related difference. Furthermore, weight loss exceeding 5 kg was more common in older patients. Of the patients who continued BIKTARVY

conclusionUnderstanding age-related patterns and gastrointestinal side effects of BIKTARVY

Indexed as

age-related patternsantiretroviral therapybictegravirBIKTARVY®emtricitabinegastrointestinal adverse effectsHIVtenofovir alafenamidetreatment outcomesweight loss

Identifiers

PMID38275565
PMCPMC10814213
OpenAlexW4390052348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.