Evidence map›Paper›PMID 38275460›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Weight Gain and Increased Body Mass Index in Patients with Hepatitis C after Eradication Using Direct-Acting Antiviral Therapy in Taiwan.

Chun-Hsien Chen, Yung-Yu Hsieh, Wei-Ming Chen, Chien-Heng Shen, Kuo-Liang Wei, Kao-Chi Chang, Yuan-Jie Ding, Sheng-Nan Lu, Chao-Hung Hung, Te-Sheng Chang

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chun-Hsien ChenDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Yung-Yu HsiehDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0001-8465-5204
Wei-Ming ChenDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0002-4949-393X
Chien-Heng ShenDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Kuo-Liang WeiDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Kao-Chi ChangDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Yuan-Jie DingDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Sheng-Nan LuCollege of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.ORCID 0000-0002-5493-4752
Chao-Hung HungCollege of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.
Te-Sheng ChangDepartment of Gastroenterology and Hepatology, Division of Internal Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0002-1581-6948

Funding

Chang Gung Memorial Hospital CMRPG6M0202
6 · The paper itself

Abstract

Few studies have reported weight gain in patients with hepatitis C virus (HCV) infection treated with direct-acting antiviral agents (DAAs). This retrospective cohort study identified factors associated with substantial weight gain after DAA treatment in Taiwan. This study involved patients treated using DAAs at the Chiayi and Yunlin branches of Chang Gung Memorial Hospital from 1 January 2017 to 31 October 2020. Body weight data were collected at the start of DAA therapy and 2 years after the confirmation of a sustained virologic response. We performed multiple logistic regression to evaluate the clinical and laboratory parameters associated with a large body mass index (BMI) increase (≥5%). The mean BMI was 25.56 ± 4.07 kg/m

Indexed as

direct-acting antiviral therapyhepatitis C virus (HCV)obesityweight gain

Identifiers

PMID38275460
PMCPMC10814234

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.