Evidence map›Paper›PMID 38275379›Full record

ArticleBiomedicines2023

Association of

Tomas Blekeris, Greta Gedvilaite, Kriste Kaikaryte, Loresa Kriauciuniene, Dalia Zaliuniene, Rasa Liutkevciene

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tomas BlekerisMedical Faculty, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Greta GedvilaiteMedical Faculty, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.ORCID 0000-0001-7469-8825
Kriste KaikaryteMedical Faculty, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.ORCID 0009-0001-3419-8997
Loresa KriauciunieneNeuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Dalia ZaliunieneOphthalmology Department, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Rasa LiutkevcieneNeuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a progressive degenerative disease that affects the central part of the retina: the macula. AMD is the most common cause of central vision loss in industrialized countries. Increasing attention is being paid to the study of genetic factors that may influence the manifestation of AMD. STAT4 protein is involved in the pathogenesis of numerous inflammatory processes, so we decided to investigate the association between PURPOSE: To investigate the association between METHODS AND

participantsThe study included 150 individuals with early AMD, 150 individuals with exudative AMD, and 200 healthy subjects. DNA was extracted from peripheral blood leukocytes using the DNA salting-out method, and the genotyping was performed using a real-time polymerase chain reaction (RT-PCR) method. STAT4 serum levels were evaluated using the ELISA method. Statistical analysis was performed using "IBM SPSS "Statistics 29.0" software".

resultsThe study revealed no statistically significant differences in the distribution of genotypes and alleles for the

conclusionInvestigating

Indexed as

age-related macular degenerationSTAT4 gene polymorphisms

Identifiers

PMID38275379
PMCPMC10813583
OpenAlexW4390038475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.