Selective and Concentrative Enteropancreatic Recirculation of Antibiotics by Pigs.

Karyl K Buddington, Stefan G Pierzynowski, William E Holmes, Randal K Buddington

Open access · goldAbstract read

In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.6field-weighted citation impact, top 27% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Karyl K BuddingtonDepartment of Biology, University of Memphis, Memphis, TN 38152, USA.

Stefan G PierzynowskiDepartment of Biology, Lund University, Sölvegatan 35, 22362 Lund, Sweden.ORCID 0000-0002-0308-3214

William E HolmesDepartment of Chemical Engineering, University of Louisiana, Lafayette, LA 70503, USA.ORCID 0000-0001-6205-3288

Randal K BuddingtonDepartment of Health Sciences, University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0001-5790-0593

Medical University of Lublin · PLStonewall Learning Center · USUniversity of Louisiana at Lafayette · USUniversity of Memphis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics that are efficacious for infectious pancreatitis are present in pancreatic exocrine secretion (PES) after intravenous administration and above minimal inhibitory concentrations. We measured concentrations of four antibiotics by tandem liquid chromatography-mass spectroscopy in plasma and PES after enteral administration to juvenile pigs with jugular catheters and re-entrant pancreatic-duodenal catheters. Nystatin, which is not absorbed by the intestine nor used for infectious pancreatitis (negative control), was not detected in plasma or PES. Concentrations of amoxicillin increased in plasma after administration (

Indexed as

antibioticductal epitheliumenteropancreatic recirculationexocrinepancreaspigsecretion

Identifiers

PMID38275322

DOI10.3390/antibiotics13010012

PMCPMC10812520

OpenAlexW4390052722

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.