Evidence map›Paper›PMID 38275309›Full record

ArticleBiosensors2024

Sensing Levofloxacin with an RNA Aptamer as a Bioreceptor.

Janice Kramat, Leon Kraus, Vincent J Gunawan, Elias Smyej, Philipp Froehlich, Tim E Weber, Dieter Spiehl, Heinz Koeppl, Andreas Blaeser, Beatrix Suess

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Janice KramatSynthetic RNA Biology, Department of Biology, Technical University of Darmstadt, 64287 Darmstadt, Germany.
Leon KrausSynthetic RNA Biology, Department of Biology, Technical University of Darmstadt, 64287 Darmstadt, Germany.
Vincent J GunawanSynthetic RNA Biology, Department of Biology, Technical University of Darmstadt, 64287 Darmstadt, Germany.
Elias SmyejSynthetic RNA Biology, Department of Biology, Technical University of Darmstadt, 64287 Darmstadt, Germany.ORCID 0009-0007-8094-3437
Philipp FroehlichSelf-Organizing Systems, Department of Electrical Engineering and Information Technology, Technical University of Darmstadt, 64283 Darmstadt, Germany.
Tim E WeberInstitute for BioMedical Printing Technologies, Technical University of Darmstadt, 64289 Darmstadt, Germany.
Dieter SpiehlInstitute for BioMedical Printing Technologies, Technical University of Darmstadt, 64289 Darmstadt, Germany.ORCID 0000-0001-9738-3025
Heinz KoepplSelf-Organizing Systems, Department of Electrical Engineering and Information Technology, Technical University of Darmstadt, 64283 Darmstadt, Germany.
Andreas BlaeserInstitute for BioMedical Printing Technologies, Technical University of Darmstadt, 64289 Darmstadt, Germany.
Beatrix SuessSynthetic RNA Biology, Department of Biology, Technical University of Darmstadt, 64287 Darmstadt, Germany.

Funding

Deutsche Forschungsgemeinschaft SU402/9-1
6 · The paper itself

Abstract

To combat the growing threat of antibiotic resistance, environmental testing for antibiotic contamination is gaining an increasing role. This study aims to develop an easy-to-use assay for the detection of the fluoroquinolone antibiotic levofloxacin. Levofloxacin is used in human and veterinary medicine and has been detected in wastewater and river water. An RNA aptamer against levofloxacin was selected using RNA Capture-SELEX. The 73 nt long aptamer folds into three stems with a central three-way junction. It binds levofloxacin with a

Indexed as

Aptamers, NucleotideAnti-Bacterial AgentsHumansLevofloxacinRNASELEX Aptamer TechniqueAnti-Bacterial AgentsAptamers, NucleotideLevofloxacinRNAantibioticsaptamersbiosensorlateral flow assaylevofloxacinSELEX

Identifiers

PMID38275309
PMCPMC10813692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.