Evidence map›Paper›PMID 38275291›Full record

ArticleOncotarget2024

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation.

Mark Lee, Luc Gt Morris

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Dual targeting of BRAFJournal of experimental & clinical cancer research : CR · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mark LeeDepartment of Otolaryngology-Head and Neck Surgery, New York Presbyterian Hospital, New York, NY 10032, USA.
Luc Gt MorrisDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Memorial Sloan Kettering Cancer Center · USNewYork–Presbyterian Hospital · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Identifying and targeting neoantigens in aggressive salivary carcinomasR01DE027738 · NIDCR · SLOAN-KETTERING INST CAN RESEARCH · PI CHAN, TIMOTHY AN-THY, HO, ALAN L. · 2018 to 2022
$2.8M
Non-canonical WNT signaling in the invasion and metastasis of uveal melanomaF30CA217184 · NCI · UNIVERSITY OF UTAH · PI RICHARDS, JACKSON ROYAL · 2017 to 2021
$206k
NCI NIH HHS F30 CA217184NCI NIH HHS P30 CA008748NIDCR NIH HHS R01 DE027738
6 · The paper itself

Abstract

A subset of thyroid cancers present at advanced stage or with dedifferentiated histology and have limited response to standard therapy. Tumors harboring the

Indexed as

Proto-Oncogene Proteins B-rafThyroid NeoplasmsCell Line, TumorHumansMutationp120 GTPase Activating ProteinPhosphatidylinositol 3-KinasesProtein Kinase InhibitorsTOR Serine-Threonine KinasesBRAF protein, humanp120 GTPase Activating ProteinPhosphatidylinositol 3-KinasesProtein Kinase InhibitorsProto-Oncogene Proteins B-rafRASA1 protein, humanTOR Serine-Threonine Kinasesanaplastic transformationBRAF inhibitorsdrug resistancePIK3CAthyroid cancer

Identifiers

PMID38275291
PMCPMC10812235
OpenAlexW4391161313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.