Evidence map›Paper›PMID 38275289›Full record

ArticleOncotarget2024

BCAS1 defines a heterogeneous cell population in diffuse gliomas.

Raquel Morales-Gallel, María José Ulloa-Navas, Patricia García-Tárraga, Ricardo Prat-Acín, Gaspar Reynés, Pedro Pérez-Borredá, Luis Rubio, Vivian Capilla-González, Jaime Ferrer-Lozano, José Manuel García-Verdugo

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Raquel Morales-Gallel *Laboratory of Comparative Neurobiology, Institute Cavanilles of Biodiversity and Evolutionary Biology, University of Valencia-CIBERNED, Valencia, Spain.
María José Ulloa-Navas *Department of Neurosurgery, Mayo Clinic, Jacksonville, FL 32224, USA.
Patricia García-TárragaLaboratory of Comparative Neurobiology, Institute Cavanilles of Biodiversity and Evolutionary Biology, University of Valencia-CIBERNED, Valencia, Spain.
Ricardo Prat-AcínDepartment of Neurosurgery, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
Gaspar ReynésGroup of Clinical and Translational Research in Cancer, Health Research Institute Hospital Universitari i Politècnic La Fe, Valencia, Spain.
Pedro Pérez-BorredáDepartment of Neurosurgery, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
Luis RubioDepartment of Pathology, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
Vivian Capilla-GonzálezDepartment of Integrative Pathophysiology and Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucía-University of Pablo de Olavide-University of Seville-CSIC, Seville, Spain.
Jaime Ferrer-LozanoDepartment of Pathology, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
José Manuel García-VerdugoLaboratory of Comparative Neurobiology, Institute Cavanilles of Biodiversity and Evolutionary Biology, University of Valencia-CIBERNED, Valencia, Spain.
Hospital Universitari i Politècnic La Fe · ESCentro de Investigación Biomédica en Red · ESMayo Clinic in Florida · USUniversidad Pablo de Olavide · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligodendrocyte precursor markers have become of great interest to identify new diagnostic and therapeutic targets for diffuse gliomas, since state-of-the-art studies point towards immature oligodendrocytes as a possible source of gliomagenesis. Brain enriched myelin associated protein 1 (BCAS1) is a novel marker of immature oligodendrocytes and was proposed to contribute to tumorigenesis in non-central nervous system tumors. However, BCAS1 role in diffuse glioma is still underexplored. This study analyzes the expression of BCAS1 in different tumor samples from patients with diffuse gliomas (17 oligodendrogliomas; 8 astrocytomas; 60 glioblastomas) and uncovers the molecular and ultrastructural features of BCAS1

Indexed as

AstrocytomaBrain NeoplasmsGlioblastomaGliomaOligodendrogliomaHumansNeoplasm ProteinsBCAS1 protein, humanNeoplasm ProteinsBCAS1brain tumordiffuse gliomaglioblastomaoligodendroglioma

Identifiers

PMID38275289
PMCPMC10812236
OpenAlexW4391161276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.