Evidence map›Paper›PMID 38275070›Full record

ArticleRecent advances in anti-infective drug discovery2024

Cholecalciferol Exhibits no Antibacterial Effect on

Shilia Jacob Kurian, Avirup Biswas, Shrivathsa Kulavalli, Jesil Mathew Aranjani, Amrita Pattanaik, Murali Munisamy, Kavitha Saravu, Gabriel Sunil Rodrigues, Sonal Sekhar Miraj

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Article in Recent advances in anti-infective drug discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Shilia Jacob KurianDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of High Education, Manipal, Karnataka, India.
Avirup BiswasDepartment of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of High Education, Manipal, Karnataka, India.
Shrivathsa KulavalliDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of High Education, Manipal, Karnataka, India.
Jesil Mathew AranjaniDepartment of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of High Education, Manipal, Karnataka, India.
Amrita PattanaikManipal Institute of Virology, Manipal Academy of High Education, Manipal, Karnataka, India.
Murali MunisamyDepartment of Translational Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Kavitha SaravuManipal Centre for Infectious Diseases, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Gabriel Sunil RodriguesConsultant General and Laparoscopic Surgeon, Aster Al Raffah Hospital, Sohar, Sultanate of Oman.
Sonal Sekhar MirajDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of High Education, Manipal, Karnataka, India.
Manipal Academy of Higher Education · INAll India Institute of Medical Sciences Bhopal · INKasturba Medical College, Manipal · INSohar University · OM

Funding

Indian Council of Medical Research (ICMR), New Delhi 3/1/3(16)/Endofellowship/21-NCD-III
6 · The paper itself

Abstract

backgroundThe pleiotropic effect of cholecalciferol (vitamin D

objectivesThe study aimed to investigate the antimicrobial effect of cholecalciferol against

methodsAn

resultsThe MIC value of cholecalciferol against both S. aureus and

conclusionThis study indicates that cholecalciferol does not directly inhibit S. aureus and E. coli. Hence, we suggest exploring the antibacterial properties of other vitamin D analogs, such as calcitriol or its synergetic effect with other antimicrobial agents.

Indexed as

Anti-Bacterial AgentsCholecalciferolEscherichia coliMicrobial Sensitivity TestsStaphylococcus aureusDimethyl SulfoxideAnti-Bacterial AgentsCholecalciferolDimethyl Sulfoxideantibacterial effect.Cholecalciferoldiabetic foot ulcersEscherichia coliStaphylococcus aureusvitamin D3

Identifiers

PMID38275070
OpenAlexW4391219800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.