Evidence map›Paper›PMID 38275069›Full record

ReviewCurrent cardiology reviews2024

Novel Strategies to Improve the Cardioprotective Effects of Cardioplegia.

Estefanie Osorio-Llanes, Jairo Castellar-López, Wendy Rosales, Yuliet Montoya, John Bustamante, Ricardo Zalaquett, Roberto Bravo-Sagua, Jaime A Riquelme, Gina Sánchez, Mario Chiong and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Current cardiology reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Cardiac preservation usingFrontiers in cardiovascular medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Estefanie Osorio-LlanesFaculty of Exact and Natural Sciences, Grupo de Investigación Avanzada en Biomedicina, Universidad Libre Barranquilla, Atlantico, Colombia.ORCID 0000-0002-8682-8874
Jairo Castellar-LópezFaculty of Exact and Natural Sciences, Grupo de Investigación Avanzada en Biomedicina, Universidad Libre Barranquilla, Atlantico, Colombia.ORCID 0000-0002-8984-7675
Wendy RosalesFaculty of Exact and Natural Sciences, Grupo de Investigación Avanzada en Biomedicina, Universidad Libre Barranquilla, Atlantico, Colombia.ORCID 0000-0002-8032-291X
Yuliet MontoyaGrupo de Dinámica Cardiovascular (GDC), Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medellin, Colombia.ORCID 0000-0002-8402-7109
John BustamanteGrupo de Dinámica Cardiovascular (GDC), Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medellin, Colombia.ORCID 0000-0002-4855-9896
Ricardo ZalaquettDepartment of Cardiovascular Diseases, Faculty of Medicine, Universidad Finis Terrae - Clínica Las Condes, Santiago, Chile.
Roberto Bravo-SaguaAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID 0000-0001-8873-8699
Jaime A RiquelmeAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID 0000-0003-0517-5697
Gina SánchezPhysiopathology Program, Institute of Biomedical Sciences (ICBM), Faculty of Medicine, University of Chile, Santiago, Chile.ORCID 0000-0001-7702-0884
Mario ChiongAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-5174-6545
Sergio LavanderoAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID 0000-0003-4258-1483
Evelyn Mendoza-TorresAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical and Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-4586-3753
Advanced Center for Chronic Diseases · CLUniversidad Libre de Colombia · COUniversidad Pontificia Bolivariana · COClínica Las Condes · CLUniversity of Chile · CL

Funding

Agencia Nacional de Investigación y Desarrollo (ANID) FONDAP 15130011 and 1523A0008, FONDECYT 11201267, Puente-ICBM-570334, FONDECYT 1220325.MINCIENCIAS-Colombia 120884468190
6 · The paper itself

Abstract

The use of cardioprotective strategies as adjuvants of cardioplegic solutions has become an ideal alternative for the improvement of post-surgery heart recovery. The choice of the optimal cardioplegia, as well as its distribution mechanism, remains controversial in the field of cardiovascular surgery. There is still a need to search for new and better cardioprotective methods during cardioplegic procedures. New techniques for the management of cardiovascular complications during cardioplegia have evolved with new alternatives and additives, and each new strategy provides a tool to neutralize the damage after ischemia/reperfusion events. Researchers and clinicians have committed themselves to studying the effect of new strategies and adjuvant components with the potential to improve the cardioprotective effect of cardioplegic solutions in preventing myocardial ischemia/reperfusion-induced injury during cardiac surgery. The aim of this review is to explore the different types of cardioplegia, their protection mechanisms, and which strategies have been proposed to enhance the function of these solutions in hearts exposed to cardiovascular pathologies that require surgical alternatives for their corrective progression.

Indexed as

Cardiac Surgical ProceduresCardioplegic SolutionsCardiotonic AgentsHeart Arrest, InducedMyocardial Reperfusion InjuryHumansCardioplegic SolutionsCardiotonic Agentsangiotensinscardiac surgerycardioplegiacardioprotectioncardiovascular diseaseischemia/reperfusion

Identifiers

PMID38275069
PMCPMC11071679
OpenAlexW4391219895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.