Evidence map›Paper›PMID 38275017›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2024

Impact of nirsevimab prophylaxis on paediatric respiratory syncytial virus (RSV)-related hospitalisations during the initial 2023/24 season in Luxembourg.

Corinna Ernst, Dritan Bejko, Leo Gaasch, Emilie Hannelas, Isaline Kahn, Charlotte Pierron, Nesrine Del Lero, Claude Schalbar, Elsa Do Carmo, Michel Kohnen and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
48.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.

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  5. Acute viral bronchiolitis before and after implementation ofThe Lancet regional health. Europe · 2026
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Corinna ErnstHealth Directorate, Luxembourg.
Dritan BejkoHealth Directorate, Luxembourg.
Leo GaaschNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Emilie HannelasNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Isaline KahnNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Charlotte PierronNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Nesrine Del LeroNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Claude SchalbarNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Elsa Do CarmoNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Michel KohnenMicrobiology department, Centre Hospitalier de Luxembourg, Luxembourg.
Emmanuelle AndlauerHospital Pharmacy department, Centre Hospitalier de Luxembourg, Luxembourg.
Pauline HublartHealth Directorate, Luxembourg.
Silvana MasiHealth Directorate, Luxembourg.
Isabel de la Fuente GarciaNational Center for Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg.
Anne VergisonHealth Directorate, Luxembourg.
Joël MossongHealth Directorate, Luxembourg.
Centre Hospitalier de Luxembourg · LULuxembourg Institute of Health · LU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After Luxembourg introduced nirsevimab immunisation against respiratory syncytial virus (RSV), estimated neonatal coverage was 84% (1,277 doses/1,524 births) in 2023. That year, paediatric RSV-related hospitalisations, especially concerning infants < 6 months old (n = 72) seemed to decrease compared to the same period in 2022 (n = 232). In 2023, hospitalised children's mean age increased (14.4 months vs 7.8 months in 2022; p < 0.001) and hospital-stay length decreased (3.2 days vs 5.1 days; p < 0.001). In infants < 6 months old, intensive-care unit admissions appeared to drop (n = 28 vs 9). This suggests that nirsevimab prophylaxis reduced severe RSV infections, particularly in infants < 6 months old, thereby alleviating healthcare strain.

Indexed as

Antibodies, Monoclonal, HumanizedRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsChildHospitalizationHumansInfantInfant, NewbornLuxembourgSeasonsAntibodies, Monoclonal, HumanizednirsevimabImmunisationLuxembourgNirsevimabPaediatric hospitalizationReal-world evidenceRespiratory Syncytial Virus

Identifiers

PMID38275017
PMCPMC10986653
OpenAlexW4391258475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.