Evidence map›Paper›PMID 38274744›Full record

ArticleFrontiers in microbiology2023

Association between gut microbiota and peptic ulcer disease, particularly gastric ulcer and duodenal ulcer: a two-sample Mendelian randomization study.

Zhenhua Dong, Kai Yu, Yuchao Xin, Xulei Gao, Fan Bu, Dingliang Zhao, Donghui Ren, Ji Lu, Daguang Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhenhua DongDepartment of Gastric and Colorectal Surgery, The First Hospital of Jilin University Changchun, Jilin, China.
Kai YuDepartment of Urology, The First Hospital of Jilin University Changchun, Jilin, China.
Yuchao XinSecond Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University Changchun, Jilin, China.
Xulei GaoSecond Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University Changchun, Jilin, China.
Fan BuDepartment of Plastic and Aesthetic Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Dingliang ZhaoDepartment of Second Urology, The First Hospital of Jilin University Changchun, Jilin, China.
Donghui RenDepartment of Urology, The First Hospital of Jilin University Changchun, Jilin, China.
Ji LuDepartment of Urology, The First Hospital of Jilin University Changchun, Jilin, China.
Daguang WangDepartment of Gastric and Colorectal Surgery, The First Hospital of Jilin University Changchun, Jilin, China.
First Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent an observational study has suggested a potential connection between gut microbiota (GM) and peptic ulcer diseases (PUDs), particularly gastric ulcer (GU) and duodenal ulcer (DU). However, the causal connection remains unsure. Methods: A two-sample Mendelian randomization (MR) is carried out to explore the connection between the GM and DU or GU. Data on the GM comes from the MiBioGend database, and GU or DU data are based on the FinnGen database. One group of single nucleotide polymorphisms (SNPs) ( Results: At the level of Conclusion: This two-sample MR indicates a causal relationship between GM and GU or DU.

Indexed as

causal inferenceduodenal ulcergastric ulcergeneticsgut microbiotaMendelian randomization study

Identifiers

PMID38274744
PMCPMC10808813
OpenAlexW4390745391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.