Evidence map›Paper›PMID 38274740›Full record

ArticleFrontiers in microbiology2023

Machine learning and feature extraction for rapid antimicrobial resistance prediction of

Yue Gao, Henan Li, Chunjiang Zhao, Shuguang Li, Guankun Yin, Hui Wang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Food science and biotechnology · 2026
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  16. Advancements in AI-driven drug sensitivity testing research.Frontiers in cellular and infection microbiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue GaoInstitute of Medical Technology, Peking University Health Science Center, Beijing, China.
Henan LiDepartment of Clinical Laboratory, Peking University People's Hospital, Beijing, China.
Chunjiang ZhaoDepartment of Clinical Laboratory, Peking University People's Hospital, Beijing, China.
Shuguang LiDepartment of Clinical Laboratory, Peking University People's Hospital, Beijing, China.
Guankun YinDepartment of Clinical Laboratory, Peking University People's Hospital, Beijing, China.
Hui WangInstitute of Medical Technology, Peking University Health Science Center, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whole-genome sequencing (WGS) has contributed significantly to advancements in machine learning methods for predicting antimicrobial resistance (AMR). However, the comparisons of different methods for AMR prediction without requiring prior knowledge of resistance remains to be conducted. Methods: We aimed to predict the minimum inhibitory concentrations (MICs) of 13 antimicrobial agents against Results: A cohort of 339 isolates was used for model construction. The average essential agreement and category agreement of the best models exceeded 90.90% (95%CI, 89.03-92.77%) and 95.29% (95%CI, 94.91-95.67%), respectively; the exceptions being levofloxacin, minocycline and imipenem. The very major error rates ranged from 0.0 to 5.71%. We applied feature selection pipelines to extract the top-ranked 11-mers to optimise training time and computing resources. This approach slightly improved the prediction performance and enabled us to obtain prediction results within 10 min. Notably, when employing these top-ranked 11-mers in an independent test dataset (120 isolates), we achieved an average accuracy of 0.96. Conclusion: Our study is the first to demonstrate that AMR prediction for

Indexed as

Acinetobacter baumanniiantimicrobial resistance predictionk-mermachine learningwhole-genome sequencing

Identifiers

PMID38274740
PMCPMC10808480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.