Evidence map›Paper›PMID 38274660›Full record

ArticleFrontiers in veterinary science2023

Case report: Intraneural perineurioma in dogs: a case series and brief literature review.

Ji-Hang Yin, Brittani Sexton, Tom Jukier, Amy B Yanke, Merrilee Holland, Andrew D Miller, Lauren Stranahan, Aline Rodrigues Hoffmann, Maninder Sandey

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ji-Hang YinDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Brittani SextonDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Tom JukierDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Amy B YankeDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Merrilee HollandDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Andrew D MillerDepartment of Population Medicine and Diagnostic Sciences, Section of Anatomic Pathology, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.
Lauren StranahanDepartment of Veterinary Pathobiology, Texas A&M School of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, United States.
Aline Rodrigues HoffmannDepartment of Veterinary Pathobiology, Texas A&M School of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, United States.
Maninder SandeyDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Auburn University · USTexas A&M University · USCornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraneural perineurioma is an exceptionally rare neoplasm in animals. This case study comprises a series of three cases and a brief literature review focusing on canine intraneural perineurioma. The pathological and immunohistochemical findings are documented, revealing that canine intraneural perineurioma frequently affects adult dogs aged between 3 and 10 years old, with a male predominance. Clinical signs associated with intraneural perineurioma in dogs include spinal pain, lameness, and paresis, resulting from the involvement of spinal nerve roots of the pelvic limbs, brachial plexus, or distal part of the median nerve. Most neoplasms had characteristic pseudo-onion bulb patterns on histopathology. Neoplastic perineurial cells, in most cases, expressed laminin and claudin-1, and NF200 consistently highlighted the central axon. While the immunohistochemical (IHC) profile of intraneural perineurioma in veterinary medicine remains incompletely characterized, the available IHC data from all reported cases suggest that a combination of laminin and claudin-1 immunomarkers, along with distinctive histological features, can assist in establishing a definitive diagnosis of intraneural perineurioma.

Indexed as

brief literature reviewcanineimmunohistochemistryintraneural perineuriomaspinal nerve roots

Identifiers

PMID38274660
PMCPMC10808598
OpenAlexW4390745219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.