Evidence map›Paper›PMID 38274402›Full record

ArticleMachine learning in medical imaging. MLMI (Workshop)2023

Radiomics Boosts Deep Learning Model for IPMN Classification.

Lanhong Yao, Zheyuan Zhang, Ugur Demir, Elif Keles, Camila Vendrami, Emil Agarunov, Candice Bolan, Ivo Schoots, Marc Bruno, Rajesh Keswani and 7 more

Open access · greenAbstract read
In one paragraph

Article in Machine learning in medical imaging. MLMI (Workshop), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  8. Pediatric pancreas segmentation from MRI scans with deep learning.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2025
    Article
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  11. Review
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  13. Detection of Peri-Pancreatic Edema using Deep Learning and Radiomics Techniques.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 5 countries.

Lanhong YaoDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Zheyuan ZhangDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Ugur DemirDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Elif KelesDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Camila VendramiDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Emil AgarunovNYU Langone Health, New York, NY 10016.
Candice BolanMayo Clinic, Rochester, MN 55905.
Ivo SchootsErasmus Medical Center, 3015 GD Rotterdam, Netherlands.
Marc BrunoErasmus Medical Center, 3015 GD Rotterdam, Netherlands.
Rajesh KeswaniDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Frank MillerDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Tamas GondaNYU Langone Health, New York, NY 10016.
Cemal YaziciUniversity of Illinois Chicago, Chicago, IL 60607.
Temel TirkesIndiana University-Purdue University Indianapolis, Indianapolis, IN 46202.
Michael WallaceSheikh Shakhbout Medical City, 11001, Abu Dhabi, United Arab Emirates.
Concetto SpampinatoUniversity of Catania, 95124 Catania CT, Italy.
Ulas BagciDepartment of Radiology, Northwestern University, Chicago IL 60611, USA.
Northwestern University · USNorthwestern University · PHNYU Langone Health · USErasmus MC · NLErasmus University Rotterdam · NLIndiana University – Purdue University Indianapolis · USMayo Clinic in Arizona · USNorthwestern Medicine · USSheikh Shakhbout Medical City · AEUniversity of Catania · ITUniversity of Illinois Chicago · US

Funding

Data Coordinating Center for the Type 1 Diabetes in Acute Pancreatitis ConsortiumU01DK127384 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Vernon M Chinchilli, Temel Tirkes · 2020 to 2026
$21.3M
Cyst-X: Interpretable Deep Learning Based Risk Stratification of Pancreatic Cystic TumorsR01CA246704 · NCI · UNIVERSITY OF CENTRAL FLORIDA · PI BAGCI, ULAS · 2020 to 2024
$2.4M
NCI NIH HHS R01 CA246704NIDDK NIH HHS U01 DK127384
6 · The paper itself

Abstract

Intraductal Papillary Mucinous Neoplasm (IPMN) cysts are pre-malignant pancreas lesions, and they can progress into pancreatic cancer. Therefore, detecting and stratifying their risk level is of ultimate importance for effective treatment planning and disease control. However, this is a highly challenging task because of the diverse and irregular shape, texture, and size of the IPMN cysts as well as the pancreas. In this study, we propose a novel computer-aided diagnosis pipeline for IPMN risk classification from multi-contrast MRI scans. Our proposed analysis framework includes an efficient volumetric self-adapting segmentation strategy for pancreas delineation, followed by a newly designed deep learning-based classification scheme with a radiomics-based predictive approach. We test our proposed decision-fusion model in multi-center data sets of 246 multi-contrast MRI scans and obtain superior performance to the state of the art (SOTA) in this field. Our ablation studies demonstrate the significance of both radiomics and deep learning modules for achieving the new SOTA performance compared to international guidelines and published studies (81.9% vs 61.3% in accuracy). Our findings have important implications for clinical decision-making. In a series of rigorous experiments on multi-center data sets (246 MRI scans from five centers), we achieved unprecedented performance (81.9% accuracy). The code is available upon publication.

Indexed as

IPMN ClassificationMRIPancreas SegmentationPancreatic CystsRadiomics

Identifiers

PMID38274402
PMCPMC10810260
OpenAlexW4387640555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.