Evidence map›Paper›PMID 38274039›Full record

ArticleeNeurologicalSci2024

Effect of istradefylline on postural abnormalities in patients with Parkinson's disease: An association study of baseline postural angle measurements with changes in Unified Dystonia Rating Scale total score.

Makio Takahashi, Toshio Shimokawa, Jinsoo Koh, Takao Takeshima, Hirofumi Yamashita, Yoshinori Kajimoto, Hidefumi Ito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeurologicalSci, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Makio TakahashiDepartment of Neurology, Kitano Hospital, The Tazuke-Kofukai Medical Research Institute, Osaka, Japan.
Toshio ShimokawaClinical Study Support Center, Wakayama Medical University, Wakayama, Japan.
Jinsoo KohDepartment of Neurology, Wakayama Medical University, Wakayama, Japan.
Takao TakeshimaDepartment of Neurology, Tominaga Hospital, Osaka, Japan.
Hirofumi YamashitaDepartment of Neurology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.
Yoshinori KajimotoDepartment of Neurology, Wakayama Medical University Kihoku Hospital, Wakayama, Japan.
Hidefumi ItoDepartment of Neurology, Wakayama Medical University, Wakayama, Japan.
Wakayama Medical University · JPJapanese Red Cross Society Wakayama Medical Center · JPKitano Hospital · JPTominaga hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our previous study, istradefylline treatment in patients with Parkinson's disease (PD) improved postural abnormalities (PAs), as seen from a decrease in the mean Unified Dystonia Rating Scale (UDRS) total score from week 0 to week 24. A subgroup analysis based on baseline clinical characteristics investigated the association between improvement in the UDRS total score and istradefylline treatment. However, the association between an objective assessment of PAs and improvement in the UDRS total score is unclear. This ad hoc analysis investigated the association between improvement in the UDRS total score after istradefylline treatment and baseline trunk and neck angles, objective assessments of PAs, measured from patients' photographs taken in the previous study. The patients (

Indexed as

Angle valueIstradefyllineParkinson's diseasePostural abnormalitiesUnified Dystonia Rating Scale

Identifiers

PMID38274039
PMCPMC10809095
OpenAlexW4390431436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.