Evidence map›Paper›PMID 38274029›Full record

ArticlePhysica D. Nonlinear phenomena2023

The power of weak, transient interactions across biology: A paradigm of emergent behavior.

Paula A Vasquez, Ben Walker, Kerry Bloom, Daniel Kolbin, Neall Caughman, Ronit Freeman, Martin Lysy, Caitlin Hult, Katherine A Newhall, Micah Papanikolas and 2 more

Open access · greenAbstract read
In one paragraph

Article in Physica D. Nonlinear phenomena, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Polarization as a Process: The Potential of Process Ontology for Understanding Cellular Symmetry Breaking.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  2. Article
  3. Article
  4. Information Transmission in G Protein-Coupled Receptors.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Paula A VasquezDepartment of Mathematics, University of South Carolina, United States of America.
Ben WalkerDepartment of Mathematics, University of California at Irvine, United States of America.
Kerry BloomDepartment of Biology, University of North Carolina at Chapel Hill, United States of America.
Daniel KolbinDepartment of Biology, University of North Carolina at Chapel Hill, United States of America.
Neall CaughmanDepartment of Mathematics, University of North Carolina at Chapel Hill, United States of America.
Ronit FreemanDepartment of Applied Physical Sciences, University of North Carolina at Chapel Hill, United States of America.
Martin LysyDepartment of Statistics and Actuarial Science, University of Waterloo, Canada.
Caitlin HultDepartment of Mathematics, Gettysburg College, United States of America.
Katherine A NewhallDepartment of Mathematics, University of North Carolina at Chapel Hill, United States of America.
Micah PapanikolasDepartment of Applied Physical Sciences, University of North Carolina at Chapel Hill, United States of America.
Christopher EdelmaierDepartment of Applied Physical Sciences, University of North Carolina at Chapel Hill, United States of America.
M Gregory ForestDepartment of Mathematics, University of North Carolina at Chapel Hill, United States of America.
University of North Carolina at Chapel Hill · USApplied Physical Sciences (United States) · USGettysburg College · USUniversity of California, Irvine · USUniversity of South Carolina · USUniversity of Waterloo · CA

Funding

Structure and Function of a Eukaryotic CentromereR01GM032238 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BLOOM, KERRY S · 1985 to 2025
$6.2M
NIGMS NIH HHS R01 GM032238
6 · The paper itself

Abstract

A growing list of diverse biological systems and their equally diverse functionalities provides realizations of a paradigm of emergent behavior. In each of these biological systems, pervasive ensembles of weak, short-lived, spatially local interactions act autonomously to convey functionalities at larger spatial and temporal scales. In this article, a range of diverse systems and functionalities are presented in a cursory manner with literature citations for further details. Then two systems and their properties are discussed in more detail: yeast chromosome biology and human respiratory mucus.

Indexed as

Biological paradigmEmergent behaviorTransient interactionsWeak

Identifiers

PMID38274029
PMCPMC10806540
OpenAlexW4385597975

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.