Evidence map›Paper›PMID 38274009›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Cas9 deletion of lutein biosynthesis in the marine alga

Melissa Cano, Anagha Krishnan, Devin A Karns, Maria A Likhogrud, Joseph C Weissman, Matthew C Posewitz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Melissa CanoDepartment of Chemistry, Colorado School of Mines, Golden, CO, United States.
Anagha KrishnanDepartment of Chemistry, Colorado School of Mines, Golden, CO, United States.
Devin A KarnsDepartment of Chemistry, Colorado School of Mines, Golden, CO, United States.
Maria A LikhogrudExxonMobil Technology and Engineering Company, Annandale, NJ, United States.
Joseph C WeissmanExxonMobil Technology and Engineering Company, Annandale, NJ, United States.
Matthew C PosewitzDepartment of Chemistry, Colorado School of Mines, Golden, CO, United States.
Colorado School of Mines · USExxonMobil (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Domestication of algae for food and renewable biofuels remains limited by the low photosynthetic efficiencies of processes that have evolved to be competitive for optimal light capture, incentivizing the development of large antennas in light-limiting conditions, thus decreasing efficient light utilization in cultivated ponds or photobioreactors. Reducing the pigment content to improve biomass productivity has been a strategy discussed for several decades and the ability to reduce pigment significantly is now fully at hand thanks to the widespread use of genome editing tools.

Indexed as

biomass productivityCRISPR/Cas9luteinPicochlorum celeripigment reduction

Identifiers

PMID38274009
PMCPMC10808502
OpenAlexW4390743425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.