Evidence map›Paper›PMID 38273970›Full record

ArticleLeukemia research reports2024

Genomic heterogeneity within B/T mixed phenotype acute leukemia in a context of an immunophenotype.

Ruifang Zheng, Franklin Fuda, Jeffrey R Gagan, Olga K Weinberg, Prasad Koduru, Miguel Cantu, Kathleen Ludwig, Jamie M Truscott, Robert Collins, Stephen Chung and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. EJHaem · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ruifang ZhengDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Franklin FudaDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Jeffrey R GaganDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Olga K WeinbergDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Prasad KoduruDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Miguel CantuDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Kathleen LudwigDepartments of Pediatrics (Hematology and Oncology), University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Jamie M TruscottDepartments of Pediatrics (Hematology and Oncology), University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Robert CollinsInternal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Stephen ChungInternal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Yazan F MadanatInternal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Weina ChenDepartments of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B/T mixed phenotype acute leukemia (MPAL) is a rare aggressive leukemia. Three cases of B/T MPAL were identified with comprehensive immunophenotypic, cytogenetic, and molecular studies. T-lineage predominant B/T MPAL shares a genetic signature with T-ALL whereas B/T lineage co-dominant B/T MPAL lacks such a T-ALL signature

Indexed as

AMLB-ALLB/T MPALGenotypeImmunophenotypeJAK/STAT pathwayMixed phenotype acute leukemiaNOTCH1PHF6RAS pathwayT-ALL

Identifiers

PMID38273970
PMCPMC10808966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.