Evidence map›Paper›PMID 38273410›Full record

ArticleBMC pharmacology & toxicology2024

Informal sale of antibiotics in Guatemalan convenience stores before and after implementation of federal antibiotic dispensing legislation.

N Rojop, P Moreno, L Grajeda, J Romero, L Reynoso, E Muñoz, G H Palmer, C Cordón-Rosales, D R Call, B M Ramay

Abstract read
In one paragraph

Article in BMC pharmacology & toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Trends inAntibiotics (Basel, Switzerland) · 2025
    Article
  3. A Decade of Antimicrobial Resistance in Human and AnimalAntibiotics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

N RojopDepartment of Epidemiology, School of Sciences and Humanities, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
P MorenoCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
L GrajedaDepartment of Epidemiology, School of Sciences and Humanities, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
J RomeroCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
L ReynosoDepartment of Pharmaceutical Chemistry, School of Sciences and Humanities, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
E MuñozDepartment of Pharmaceutical Chemistry, School of Sciences and Humanities, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
G H PalmerPaul G. Allen School for Global Health, Washington State University, Pullman, WA, United States of America.
C Cordón-RosalesCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
D R CallPaul G. Allen School for Global Health, Washington State University, Pullman, WA, United States of America.
B M RamayCenter for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala. bramay@uvg.edu.gt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConvenience stores in Guatemala provide essential consumer goods in communities, but many dispense antibiotics illegally. Federal legislation, passed in August of 2019, requires prescriptions for antibiotic purchase at pharmacies but it is unclear if this legislation is enforced or if it has any impact on unlawful sales of antibiotics.

methodsTo determine if antibiotic availability changed in convenience stores, we carried out a repeated measures study collecting antibiotic availability data before and after implementation of the dispensing regulation.

resultsThere was no statistical difference in the proportion of convenience stores that sold antibiotics before and after antibiotic regulations [66.6% (295/443) and 66.7% (323/484), respectively, P>0.96], nor in the number of stores selling amoxicillin [55.5% (246/443) and 52.3% (253/484), respectively, P>0.96], but fewer stores (20%) sold tetracycline capsules after regulation was passed (P<0.05). For stores visited both before and after passage of legislation (n=157), 15% stopped selling antibiotics while 25% started selling antibiotics. Antibiotics from convenience stores were reportedly sold for use in people and animals.

conclusionsAntibiotics remain widely available in convenience stores consistent with no significant change in the informal sector after implementation of prescription requirements for pharmacies. Importantly, effects from regulatory change could have been masked by potential changes in antibiotic use during the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic.

Indexed as

Anti-Bacterial AgentsPharmaciesAmoxicillinCommerceDrug PrescriptionsHumansTetracyclineAmoxicillinAnti-Bacterial AgentsTetracyclineAntibioticsConvenience storesOver-the-counter availabilityPrescription

Identifiers

PMID38273410
PMCPMC10809560

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.