SynthesisBMC oral health2024
Is there a rise of prevalence for Molar Incisor Hypomineralization? A meta-analysis of published data.
Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Prevalence and association of Molar Incisor Hypomineralization (MIH) in patients presenting dental fluorosis: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Epidemiological trends in enamel hypomineralisation and molar-incisor hypomineralisation: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Increasing Diagnosis of Enamel Hypomineralisation in a Sample of More Than 70 000 Children in the City of Zurich: Repeated Cross-Sectional Prevalence Analyses and a Retrospective Longitudinal Cohort Analysis.International journal of paediatric dentistry · 2026Observational
- Oral health of incarcerated young people: a scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Dental Rehabilitation Improves Oral Health-Related Quality of Life in Children with Molar-Incisor Hypomineralisation: A 12-Month Prospective Controlled Study.Children (Basel, Switzerland) · 2026Article
- Trends in the prevalence of molar incisor hypomineralisation between 2018 and 2023: a comparison of two cross-sectional studies in elementary schools in Mexico.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Benzo[a]pyrene exposure affect the formation of dental hard tissue via the regulation of glycerophospholipid metabolism.BMC oral health · 2026Article
- Severity and extent of hypomineralised defects located on working and balancing cusps: a comparative study between primary and permanent teeth.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- The association of caries prevalence and experience in relation with molar incisor hypomineralisation and its associated factors in Mexican schoolchildren: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Clinical significance of residual yellow-brown enamel opacities in severe molar incisor hypomineralisation: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Preliminary Resin Infiltration of Hypomineralised Enamel for Posterior Indirect Adhesive Restoration: An Innovative Approach.Australian dental journal · 2026Article
- Prevalence, defect characteristics and risk factors associated with molar incisor hypomineralisation in Mexican schoolchildren: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Article
- Dental tissue fractures and their relationship with deciduous molar hypomineralization, molar incisor hypomineralization, and psychosomatic factors: a cross-sectional study.Brazilian oral research · 2026Article
- Prevalence, clinical characteristics, and associated factors of molar-incisor hypomineralisation among schoolchildren: a cross-sectional study in the Vietnamese Northern provinces.Scientific reports · 2025Article
- Children with unilateral molar-incisor hypomineralisation (MIH) may exhibit contralateral temporalis and masseter muscle hyperactivity: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Observational
- Six-year survival and clinical performance of glass hybrid restorations following selective caries removal in teeth with molar incisor hypomineralization: a prospective cohort study.Clinical oral investigations · 2025Article
- Aetiological factors in molar incisor hypomineralisation: a case-control study from Salamanca, Spain.Italian journal of pediatrics · 2025Observational
- Prevalence, clinical presentation and risk factors of molar incisor hypomineralisation and hypomineralised second primary molars among children in Buraydah, Saudi Arabia: A cross-sectional study.Journal of public health research · 2025Article
- Risk for molar incisor hypomineralization in children with hypomineralizations in the deciduous dentition: a case-control study on children from a Swiss suburban region.BMC oral health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since Molar Incisor Hypomineralization was first described as a pathologic entity, public perception often suggests a considerable rise in prevalence of the respective disease. Since there are still considerable doubts regarding the etiology and-accordingly-prevention of MIH and respective therapeutic approaches are difficult this question is of considerable clinical and public interest. Accordingly, a systematic literature search in accordance with the PRISMA guidelines for systematic reviews on Medline, Cochrane Database, EMBASE, LILACS, Web of Science, Google scholar, Scopus was performed to retrieve original articles reporting the prevalence of MIH as defined by the European Academy of Pediatric Dentistry (EAPD). From initially 2360 retrieved titles, 344 full texts were assessed for possible inclusion and finally 167 articles of mainly moderate to high quality and based on data of 46'613 individuals were included in the meta-analysis. All studies published before 2001 had to be excluded since it was not possible to align the findings with the EAPD classification. Studies varied considerably regarding cohort size (25 to 23'320, mean 1'235)) and age (5.6-19 y, mean 9.8 y). Over all studies, the weighted mean for the prevalence for MIH was 12.8% (95% CI 11.5%-14.1%) and no significant changes with respect to either publication year or birthyear were found. A sub-analysis of eleven studies reporting on the prevalence in different age groups, however, revealed strong evidence for an increasing prevalence between the years 1992 (3%) and 2013 (13%).Therefore, based on data from cross-sectional studies a possible rise in prevalence of MIH remains unclear. Future prospective large-scale studies under standardized examination conditions with an emphasis on examiner calibration are needed to gain better understanding in the evolution of the prevalence of MIH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.