ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2024
Pulsed field ablation and cryoballoon ablation for pulmonary vein isolation: insights on efficacy, safety and cardiac function.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Pulsed-Field Ablation for Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis.Journal of cardiovascular electrophysiology · 2026Pooled it
- Safety and efficacy of the pulsed field ablation for persistent atrial fibrillation: a meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Pulsed field ablation versus cryoballoon ablation for pulmonary vein isolation in atrial fibrillation: a systematic review and meta-analysis with subgroup analyses by AF type.BMC cardiovascular disorders · 2026Pooled it
- Meta-analysis of the safety and efficacy between pulsed field ablation vs. traditional ablation for persistent atrial fibrillation.Frontiers in cardiovascular medicine · 2026Pooled it
- Pulsed Field Ablation Versus Thermal Ablation for First-Time Pulmonary Vein Isolation in Atrial Fibrillation: A Systematic Review and Meta-Analysis.Journal of arrhythmia · 2026Article
- A network meta-analysis of comparative effectiveness and safety of pulsed field, radiofrequency, and cryoballoon ablation for atrial fibrillation.Heart rhythm O2 · 2026Article
- Outcomes of Pulsed Field Versus Cryoballoon Ablation in Atrial Fibrillation: A Comprehensive Systematic Review and Meta-Analysis.Journal of arrhythmia · 2026Article
- Association between T cell exhaustion and the recurrence of atrial fibrillation after cryoballoon ablation.Frontiers in immunology · 2026Article
- Pulsed-field ablation beyond pulmonary vein for persistent atrial fibrillation: efficacy and impact on left atrial function.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Controversy: pulsed field ablation is the standard technique for all the candidates for atrial fibrillation ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Review
- The relationship between systemic immune-inflammation index and recurrence after cryoballoon ablation for paroxysmal atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Thermal and Non-Thermal Energies for Atrial Fibrillation Ablation.Journal of clinical medicine · 2025Review
- Effectiveness and Safety of Pulsed Field Ablation in Patients With Atrial Fibrillation.JACC. Asia · 2025Article
- Impact of overweight and obesity on radiation dose and outcome in patients undergoing pulmonary vein isolation by cryoballoon and pulsed field ablation.International journal of cardiology. Heart & vasculature · 2024Article
- Pulsed-field ablation versus thermal ablation for atrial fibrillation: A meta-analysis.Heart rhythm O2 · 2024Review
- Efficacy and safety of pulsed field ablation compared to cryoballoon ablation in the treatment of atrial fibrillation: a meta-analysis.European heart journal open · 2024Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary vein isolation (PVI) has become the cornerstone treatment of atrial fibrillation (AF). While in cryoablation cell damage is caused by thermal effects, lately, pulsed field ablation (PFA) has been established as a novel non-thermal tissue-specific ablation modality for PVI. However, data comparing outcomes of patients undergoing either PFA or cryoballoon ablation (CBA) for primary PVI are sparse.
methodsConsecutive patients with AF undergoing PVI by either CBA or PFA were included in the analysis. The primary outcome was the time to AF/AT recurrence. For secondary outcomes, clinical and periprocedural parameters were compared.
resultsIn total, outcomes of 141 AF patients treated by PFA (94 patients) or CBA (47 patients) were compared. After 365 days, 70% of patients in the PFA group and 61% of patients in the CBA group were free from AF/AT (HR 1.35, 95% CI 0.60-3.00; p = 0.470). No deaths occurred. While symptoms alleviated in both groups, only after PFA, we observed significant improvement of left atrial volume index (PFA group baseline: 40 [31;62] ml/m
conclusionIn our study, we show that CBA and PFA for PVI are of similar efficacy when it comes to AF recurrence. However, our findings suggest that PFA rather than CBA might induce left atrial reverse remodeling thereby contributing to left ventricular systolic function.
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