ReviewMolecular psychiatry2024
Autism spectrum disorder in ICD-11-a critical reflection of its possible impact on clinical practice and research.
Review in Molecular psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between autism and psychosis and the tools used to measure it: An updated systematic review and meta-analysis.The British journal of clinical psychology · 2026Pooled it
- AI and neuroimaging in autism spectrum disorder: advances in diagnosis, methodological challenges and future directions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- [Focusing on profound autism: validity of clinical taxonomy and management of treatment-resistant symptoms].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Review
- Umbrella Review: Mental Health Interventions for Autistic Children and Adolescents: An Overview of Systematic Reviews and Participatory Equity Synthesis.JAACAP open · 2026Review
- Tracking daily activities with ecological momentary assessment: A bibliometric analysis of current use in health Mapping daily activities with ecological momentary assessment.PLOS digital health · 2026Article
- Acoustic analysis of vowel production in adults with autism spectrum disorder: beyond the notion of a unitary autistic voice.Frontiers in psychology · 2026Article
- Asymmetric developmental bifurcations in polarized environments: a new class of human variants, which may include autism.Molecular psychiatry · 2025Review
- Review of Autism Spectrum Disorder (ASD): Epidemiology, Aetiology, Pathology, and Pharmacological Treatment.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Entropy and Complexity in QEEG Reveal Visual Processing Signatures in Autism: A Neurofeedback-Oriented and Clinical Differentiation Study.Brain sciences · 2025Article
- Pathways to autism diagnosis in adulthood.Journal of neurodevelopmental disorders · 2025Article
- Plasma Metabolic and Inflammatory Protein Signatures in Psychiatric Disorders.International journal of molecular sciences · 2025Article
- Review: Child Psychiatry in the Era of Genomics: The Promise of Translational Genetics Research for the Clinic.JAACAP open · 2025Review
- Latest clinical frontiers related to autism diagnostic strategies.Cell reports. Medicine · 2025Review
- Unraveling the Connections: Eating Issues, Microbiome, and Gastrointestinal Symptoms in Autism Spectrum Disorder.Nutrients · 2025Review
- The Psychological Journey of Patients with Atrophic Acne Scarring: A Qualitative Study Based on Uncertainty in Illness Theory.Clinical, cosmetic and investigational dermatology · 2025Article
- Clinical practice guidelines for cognitive impairment in Autism spectrum disorder - Assessment and management.Indian journal of psychiatry · 2025Article
- Religiosity of adults on the autism spectrum: a cognitive and empirical analysis.Frontiers in psychiatry · 2025Article
- Decoding the peripheral transcriptomic and meta-genomic response to music in autism spectrum disorder via saliva-based RNA sequencing.Frontiers in molecular biosciences · 2025Article
- Assessment of the educational sensory-based approach for dental treatment of children with autism in Central Italy.Frontiers in oral health · 2025Article
- An entropic explanation of insistence on sameness in autism.Frontiers in computational neuroscience · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This perspective article compares and contrasts the conceptualization of Autism Spectrum Disorder (ASD) in ICD-11 and DSM-5. By guiding the user through the ICD-11 text, it is argued that, in contrast to DSM-5, ICD-11 allows a high variety in symptom combinations, which results in an operationalization of ASD that is in favor of an extreme diverse picture, yet possibly at the expense of precision, including unforeseeable effects on clinical practice, care, and research. The clinical utility is questionable as this conceptualization can hardly be differentiated from other mental disorders and autism-like traits. It moves away from an observable, behavioral, and neurodevelopmental disorder to a disorder of inner experience that can hardly be measured objectively. It contains many vague and subjective concepts that lead to non-falsifiable diagnoses. This bears a large danger of false positive diagnoses, of further increased prevalence rates, limitations of access to ASD-specific services and of increasing the non-specificity of treatments. For research, the hypothesis is that the specificity of ASD will be reduced and this will additional increase the already high heterogeneity with the effect that replication of studies will be hampered. This could limit our understanding of etiology and biological pathways of ASD and bears the risk that precision medicine, i.e., a targeted approach for individual treatment strategies based on precise diagnostic markers, is more far from becoming reality. Thus, a more precise, quantitative description and more objective measurement of symptoms are suggested that define the clinical ASD phenotype. Identification of core ASD subtypes/endophenotypes and a precise description of symptoms is the necessary next step to advance diagnostic classification systems. Therefore, employing a more finely grained, objective, clinical symptom characterization which is more relatable to neurobehavioral concepts is of central significance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.