ReviewNature reviews. Disease primers2024
Strongyloidiasis.
Review in Nature reviews. Disease primers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Prevalence of Strongyloides stercoralis infection among African children: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2026Pooled it
- Diagnostic accuracy of nucleic acid amplification tests for human intestinal nematode infections: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2026Pooled it
- IvermectinParasitology · 2024Pooled it
- Impact of mass drug administration with ivermectin, diethylcarbamazine, and albendazole for lymphatic filariasis on hookworm and Strongyloides stercoralis infections in Papua New Guinea.PLoS neglected tropical diseases · 2025Trial
- Diagnostic Accuracy of a Novel Chemiluminescent Immunoassay forDiagnostics (Basel, Switzerland) · 2026Article
- Recurrent mycotic aortic aneurysm withJournal of vascular surgery cases and innovative techniques · 2026Article
- Circulating Leukocytes and Antibody Isotype Reactivity in Rats Experimentally Infected with Different Burdens ofTropical medicine and infectious disease · 2026Article
- Intestinal Parasitic Infections and Respiratory Morbidity in Children with Sickle Cell Disease in French Guiana: A Multicenter Cross-Sectional Study.Tropical medicine and infectious disease · 2026Article
- A case of severe strongyloidiasis complicating immunosuppressive therapy initiated for IgA vasculitis.Parasites, hosts and diseases · 2026Article
- Development of Recombinase Polymerase Amplification and CRISPR-Cas12a-Enhanced Isothermal Amplification Assays for Strongyloides stercoralis DNA Detection: A Pilot Study.The American journal of tropical medicine and hygiene · 2026Article
- Molecular characterisation of extracellular vesicles released by Strongyloides stercoralis infective larvae isolated from a clinical sample.Parasites & vectors · 2026Article
- Co-endemicity of Opisthorchis viverrini and Strongyloides stercoralis infections: evidence from stool examination and serology screening in Champasak Province, Southern Lao People's Democratic Republic.Parasitology research · 2026Article
- Expanded molecular evidence of soil-transmitted helminth and Schistosoma spp. infections in Myanmar schoolchildren: A qPCR update.PLoS neglected tropical diseases · 2026Article
- In-silico design of a multi-epitope vaccine candidate against Strongyloides stercoralis.BMC infectious diseases · 2026Article
- Tropical infectious diseases and skin manifestations: a diagnostic framework.Current opinion in infectious diseases · 2026Review
- Predictors of severe strongyloidiasis and mortality in hospitalized patients from Southern Thailand.PLoS neglected tropical diseases · 2026Article
- Strongyloides Genetic Diversity among Humans, Dogs, and Nonhuman Primates, Central African Republic, 2016-2022.Emerging infectious diseases · 2026Article
- An Agar-Free, Glass Bead-Based Method for the Culture ofDiagnostics (Basel, Switzerland) · 2026Article
- Towards effective coverage of Chagas disease: a community-based approach in migrant populations.International journal for equity in health · 2026Article
- Case Report: From chronic infection to disseminated strongyloidiasis: a case of corticosteroid-induced hyperinfection syndrome.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strongyloidiasis is a neglected tropical disease caused primarily by the roundworm Strongyloides stercoralis. Strongyloidiasis is most prevalent in Southeast Asia and the Western Pacific. Although cases have been documented worldwide, global prevalence is largely unknown due to limited surveillance. Infection of the definitive human host occurs via direct skin penetration of the infective filariform larvae. Parasitic females reside in the small intestine and reproduce via parthenogenesis, where eggs hatch inside the host before rhabditiform larvae are excreted in faeces to begin the single generation free-living life cycle. Rhabditiform larvae can also develop directly into infectious filariform larvae in the gut and cause autoinfection. Although many are asymptomatic, infected individuals may report a range of non-specific gastrointestinal, respiratory or skin symptoms. Autoinfection may cause hyperinfection and disseminated strongyloidiasis in immunocompromised individuals, which is often fatal. Diagnosis requires direct examination of larvae in clinical specimens, positive serology or nucleic acid detection. However, there is a lack of standardization of techniques for all diagnostic types. Ivermectin is the treatment of choice. Control and elimination of strongyloidiasis will require a multifaceted, integrated approach, including highly sensitive and standardized diagnostics, active surveillance, health information, education and communication strategies, improved water, sanitation and hygiene, access to efficacious treatment, vaccine development and better integration and acknowledgement in current helminth control programmes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.